Fatty Acid Mixture Modulates Inflammatory Mediators

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current treatments for inflammatory pathologies, such as rheumatoid arthritis and chronic ulcerative colitis, often lead to chronic side effects and are insufficient in managing inflammatory processes effectively, necessitating the development of alternative compounds that can modulate the inflammatory response without adverse effects.

Innovation Solution

A mixture of specific fatty acids, including palmitic acid, oleic acid, stearic acid, linoleic acid, alpha-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid, is used to modulate the inflammatory process by regulating the activity of cells involved in inflammation, providing improved control and reducing side effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional treatments are used to manage inflammatory processes, then anti-inflammatory effects are achieved, but chronic side effects occur

Engineering Contradiction:
Improveanti-inflammatory effectVSAvoidchronic side effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The invention changes the chemical composition parameters by using a specific mixture of fatty acids (containing omega-3, omega-6, and omega-9 fatty acids) with defined ratios, replacing conventional anti-inflammatory drugs to achieve therapeutic effects without their associated side effects

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention employs a composite mixture of multiple fatty acid types (omega-3, omega-6, and omega-9) in specific proportions, creating a synergistic composition that provides effective anti-inflammatory action while avoiding the harmful effects of single-agent conventional treatments

Inventive Principle:
Principle #40Composite materials

2Reliability

If current treatments are used for inflammatory pathologies, then some control is achieved, but the treatments are insufficient in managing inflammatory processes effectively

Engineering Contradiction:
Improvecontrol of inflammatory processVSAvoideffectiveness in managing inflammatory processes
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The invention optimizes the composition parameters of fatty acids with specific ratios of omega-3, omega-6, and omega-9 fatty acids, enhancing the effectiveness of inflammatory process management beyond what conventional treatments achieve

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS11020365B2Mixture of fatty acids for use in the treatment of inflammatory pathologies
Publication Date: 2021.06.01 AGAIN LIFE ITAL SRL
  • US11020365B2 patent drawing
  • US11020365B2 patent drawing
  • US11020365B2 patent drawing

AI summary

This invention relates to a mixture of at least three fatty acids selected from palmitic acid, oleic acid, stearic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), azelaic acid and myristic acid. This invention also relates to the use of the aforesaid mixture in the treatment of inflammatory pathologies.