Fatty Ammonium Salt Starch Complexes for Antimicrobial Protection

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Solution Overview

Problem

Current methods lack effective solutions for inhibiting microbial growth on surfaces and deterring insect consumption of wood, particularly in agricultural and wood treatment contexts, where traditional antimicrobial agents may not provide sufficient protection against a broad range of microorganisms and pests.

Innovation Solution

Development of fatty-ammonium salt-starch inclusion complexes, combined with film-forming agents like poly(vinyl) alcohol (PVOH) and plasticizers, which form antimicrobial films that can be applied to surfaces to prevent microbial growth and deter insect consumption.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional antimicrobial agents are used, then microbial growth inhibition is achieved, but broad-spectrum protection against multiple microorganisms and pests is insufficient

Engineering Contradiction:
Improveantimicrobial protection effectivenessVSAvoidbroad-spectrum protection range
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines starch (biodegradable polysaccharide) with fatty ammonium salts (quaternary ammonium compounds) to create a composite antimicrobial material. This composite structure leverages the biocompatibility of starch and the broad-spectrum antimicrobial properties of fatty ammonium salts, achieving both effective microbial inhibition and versatile protection against multiple pathogens and pests while maintaining environmental friendliness

Inventive Principle:
Principle #40Composite materials

2Productivity

If biodegradable materials are used for wound dressings, then environmental compatibility is improved, but antimicrobial durability may be reduced

Engineering Contradiction:
Improvebiodegradability and environmental compatibilityVSAvoidantimicrobial durability
Core Design Contradiction:
ProductivityVSDuration of action of stationary object

Solution Approach 1:

The patent merges the biodegradable starch matrix with durable fatty ammonium salt antimicrobial agents to create a wound dressing that maintains both environmental compatibility and prolonged antimicrobial activity. The starch provides biocompatibility and controlled release, while the fatty ammonium salts deliver sustained broad-spectrum protection, resolving the contradiction between biodegradability and durability

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The fatty-ammonium salt-starch inclusion complexes effectively inhibit microbial growth on various surfaces and reduce wood consumption by insects, demonstrating high antimicrobial activity and durability in practical applications.

Implementation Method 1

amylose can form inclusion complexes with hydrophobic ligands such as fatty acids and fatty amines

Methodology Applied
Scientific EffectHydrophobic interaction: Hydrophobe

Implementation Method 2

the hydrophobic portion of a ligand associates with the hydrophobic internal cavity of the amylose helix by van der Waals forces

Methodology Applied
Scientific EffectVan der Waals forces: Van der Waals Force

Implementation Method 3

The fatty-ammonium salt-starch inclusion complexes effectively inhibit microbial growth on various surfaces and reduce wood consumption by insects, demonstrating high antimicrobial activity and durability in practical applications

Methodology Applied
Scientific EffectAntimicrobial activity:

Data Source

PatentUS20230127686A1Fatty ammonium salt starch complexes as plant wound protectants and antimicrobials for wound dressings
Publication Date: 2023.04.27 THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
  • US20230127686A1 patent drawing
  • US20230127686A1 patent drawing
  • US20230127686A1 patent drawing

AI summary

Provided herein are fatty-ammonium salt/starch inclusion complexes comprising one or more of a variety of fatty amines. Such complexes can be combined with film-forming agents, such as poly(vinyl) alcohol (PVOH) and plasticizing agents. The inclusion complexes of the present invention can be utilized as antimicrobial agents, preventing microbial growth on organic and inorganic surfaces. In specific embodiments, inclusion complexes of the present invention are applied to vegetable or fruit surfaces in order to impede microbial growth. Inclusion complexes of the present invention can be applied to wood in order to impede microbial growth and insect consumption and to wound dressings.