Maize Inbred FB6455 CMS Hybrid Seed Production

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Solution Overview

Problem

Corn breeding faces challenges in producing high-yielding, agronomically sound plants that are uniformly adapted across the U.S. Corn Belt, as regional growing conditions and specific issues like Gray Leaf Spot infection, cool temperatures, and soil pH levels require tailored traits in hybrids, which are often not uniformly adapted.

Innovation Solution

The development of the maize variety FB6455, which includes specific traits such as increased water stress resistance, waxy starch, male sterility, and disease resistance, introduced through transgenes, allowing for the production of hybrid seeds and plants adapted to various Corn Belt regions using methods like backcrossing and marker-assisted selection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If inbred lines are used for hybrid seed production, then uniformity and reproducibility of hybrid plants are improved, but seed production becomes difficult due to decreased vigor

Engineering Contradiction:
Improveuniformity of hybrid plantsVSAvoidseed production capability
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent introduces a male sterility system as an intermediary mechanism to resolve the contradiction. By using cytoplasmic male sterile (CMS) lines as the female parent, the system eliminates the need for manual emasculation while maintaining hybrid uniformity. The male sterile trait acts as a mediator that enables efficient hybrid seed production without compromising plant vigor or uniformity.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Strength

If hybrids are developed to achieve robust and vigorous plants, then plant vigor and yield are improved, but adaptability to specific regional conditions decreases

Engineering Contradiction:
Improveplant vigorVSAvoidregional adaptability
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The patent applies local quality by developing region-specific hybrid combinations tailored to different Corn Belt conditions. Instead of a single universal hybrid, the system creates specialized hybrids with optimized trait combinations for specific regions (e.g., northern vs. southern Corn Belt), allowing each hybrid to be locally adapted while maintaining vigor through heterosis.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent segments the Corn Belt into different regional zones and develops distinct hybrid combinations for each zone. This segmentation allows breeders to optimize for regional-specific stresses (e.g., Gray Leaf Spot in the east, cool temperatures in the north) while maintaining the overall hybrid vigor framework.

Inventive Principle:
Principle #1Segmentation

3Device complexity

If traditional breeding methods are used, then breeding process is simpler, but productivity and time efficiency of developing new varieties decrease

Engineering Contradiction:
Improvebreeding process complexityVSAvoidbreeding efficiency
Core Design Contradiction:
Device complexityVSProductivity

Solution Approach 1:

The patent replaces traditional mechanical/me manual breeding methods with molecular marker-assisted selection. Instead of relying on phenotypic observation and manual selection, the system uses DNA markers to track and select for desirable traits, dramatically increasing breeding efficiency and reducing the time required to develop new varieties.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements feedback mechanisms through molecular marker screening at multiple stages of the breeding process. By continuously monitoring genetic markers associated with desirable traits, the system provides real-time feedback to guide selection decisions, accelerating the breeding cycle and improving the precision of trait incorporation.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS9730410B2Variety corn line FB6455
Publication Date: 2017.08.15 SYNGENTA CROP PROTECITON AG

AI summary

The present invention provides an inbred corn line designated FB6455, methods for producing a corn plant by crossing plants of the inbred line FB6455 with plants of another corn plant. The invention further encompasses all parts of inbred corn line FB6455, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line FB6455, and plants produced according to these methods.