FDCA Production from Aldaric Acids via Acid Catalysis

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Solution Overview

Problem

Current methods for producing 2,5-furan dicarboxylic acid (FDCA) face challenges such as the difficulty in isolating hydroxymethyl furfural (HMF) due to its low volatility and low decomposition temperature, and the inefficiency of oxidizing HMF to FDCA, which requires precious metal catalysts and controlled pH conditions, making commercial production unfeasible.

Innovation Solution

A method involving the dehydration and cyclization of 6-carbon aldaric acids, derived from renewable biomass sources like pectin and alginate, using acid catalysis to form FDCA, which avoids the use of HMF and employs sulfuric acid or ionic liquids as catalysts, allowing for the production of FDCA with superior vapor barrier properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If HMF is used as an intermediate in FDCA production, then the dehydration pathway is established, but isolation becomes difficult due to low volatility and low decomposition temperature

Engineering Contradiction:
Improveisolation of intermediateVSAvoidstability of intermediate
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent removes HMF from the process pathway entirely, extracting the problematic intermediate step. Instead of dehydrating glucose to HMF and then oxidizing it, the method directly oxidizes glucose to FDCA, eliminating the isolation and handling of HMF and its associated problems with low volatility and decomposition.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The conventional sequence is inverted: instead of dehydration first then oxidation, the patent performs oxidation first (glucose to FDCA) without forming HMF. This reverses the traditional pathway and avoids creating the problematic intermediate compound altogether.

Inventive Principle:
Principle #13The other way round (Inversion)

2Productivity

If HMF oxidation is used to produce FDCA, then FDCA can be formed, but precious metal catalysts and controlled pH conditions are required making the process inefficient

Engineering Contradiction:
Improveoxidation efficiencyVSAvoidcatalyst requirements
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent replaces expensive precious metal catalysts with a simpler, more economical catalyst system. The method uses readily available catalysts that do not require the same level of pH control and maintenance, making the process more suitable for commercial production.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent changes the reaction parameters significantly - operating at higher pH conditions (alkaline environment) compared to the acidic conditions required for HMF oxidation. This parameter change enables the use of different catalyst systems that are more efficient and less complex.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If sulfuric acid is used as catalyst in FDCA ester formation, then the reaction proceeds readily, but dibutyl sulfate forms consuming the catalyst and quenching the reaction

Engineering Contradiction:
Improvereaction rateVSAvoidcatalyst consumption
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The patent addresses the side reaction problem by using ionic liquids as catalysts. The ionic liquid catalyst system is designed to minimize or prevent the formation of dibutyl sulfate, converting a potentially harmful side reaction into a controlled process where the catalyst remains stable and active throughout the reaction.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent employs ionic liquids as a composite catalyst system that combines catalytic activity with stability. These ionic liquids are designed to resist formation of unwanted byproducts like dibutyl sulfate, maintaining catalyst integrity and preventing quenching of the reaction.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enables the efficient production of FDCA with higher yields and improved properties, suitable for use in polyalkylene furoate polymers, potentially replacing traditional polyethylene terephthalate in packaging applications, and provides a value-added use for agricultural byproducts that would otherwise be waste.

Implementation Method 1

dehydrating and cyclizing the aldaric acid in the reaction medium (e.g., under temperature and pressure conditions suitable to drive the acid catalysis of the dehydration and cyclization reactions) to form 2,5-furan dicarboxylic acid (FDCA)

Methodology Applied
Scientific EffectAcid catalysis: Catalysis

Data Source

PatentUS9994539B2Formation of 2,5-furan dicarboxylic acid from aldaric acids
Publication Date: 2018.06.12 BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIV

AI summary

The disclosure relates to a method for forming 2,5-furan dicarboxylic acid (FDCA) from aldaric acids. The aldaric acids are dehydrating and cyclizing via acid catalysis to form the FDCA product. Aldaric acids such as galactaric acid, gularic acid, mannaric acid, and glucaric acid can be used in the disclosed method, and the aldaric acids can be obtained from form renewable biomass sources which contain pectin, alginate, and/or other biomass carbohydrates. The FDCA can be used as a renewable feedstock for consumer product polymeric materials such as polyalkylene furoate polymers.