FDOCT System Rapid Mode Switching for Extended Ocular Imaging Depth

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Solution Overview

Problem

Frequency domain optical coherence tomography (FDOCT) systems face limitations in imaging depth and sensitivity due to complex conjugate artifacts and sensitivity falloff, which restrict their application in ophthalmology, particularly in imaging deeper ocular structures without confounding mirror image artifacts or signal degradation.

Innovation Solution

The system rapidly switches between scanning modes to adjust focal optics and reference delays, incorporating techniques like phase modulation and comb filters to enhance imaging depth and reduce artifacts, allowing for deeper and more comprehensive ocular imaging without the need for external adapters.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Length of stationary object

If FDOCT systems use standard imaging depth settings, then imaging speed and resolution are maintained, but imaging depth is limited due to complex conjugate artifacts and sensitivity falloff

Engineering Contradiction:
Improveimaging depthVSAvoidcomplex conjugate artifacts and sensitivity falloff
Core Design Contradiction:
Length of stationary objectVSObject-generated harmful factors

Solution Approach 1:

The system dynamically switches between different scanning modes (anterior segment mode and retinal mode) and adjusts reference delays in real-time. The focal optics are rapidly switched between modes in less than 1.0 second, and the reference arm is configured to adapt to the focal optics of at least two scanning modes, enabling the system to overcome the static limitations of standard FDOCT imaging depth settings.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The imaging process is divided into distinct scanning modes: anterior segment scanning mode for imaging structures like the cornea and lens, and retinal scanning mode for imaging the retina. Each mode has optimized reference delays and focal optics configurations. This segmentation allows the system to achieve extended imaging depth by treating different ocular regions with mode-specific parameters, thereby reducing complex conjugate artifacts in each segment.

Inventive Principle:
Principle #1Segmentation

2Adaptability or versatility

If the system switches between multiple scanning modes, then comprehensive ocular imaging is enabled, but system complexity increases

Engineering Contradiction:
Improvescanning mode adaptabilityVSAvoidoptical switching mechanism
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The reference arm is designed with multi-functionality to adapt to focal optics of at least two scanning modes. A single reference arm configuration can serve both anterior segment and retinal imaging modes by rapidly adjusting reference delays, eliminating the need for separate reference arms for each mode. This universal design reduces overall system complexity while maintaining versatility.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system replaces complex mechanical switching mechanisms with rapid electronic control of focal optics switching. The focal optics are switched between scanning modes in less than 1.0 second using electronically controlled mechanisms rather than complex mechanical adapters, reducing mechanical complexity while maintaining mode-switching capability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Adaptability or versatility

If external adapters are used to switch scanning modes, then mode switching is achieved, but ease of operation deteriorates

Engineering Contradiction:
Improvescanning mode switchingVSAvoidadapter installation and switching
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The system performs self-service by automatically switching between scanning modes based on the imaging target. The control system automatically selects the appropriate scanning mode (anterior segment or retinal) and adjusts reference delays without requiring manual intervention or external adapters. This automated mode switching significantly improves ease of operation while maintaining full adaptability.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables extended depth imaging, quadrupling the available imaging depth while maintaining axial resolution, facilitating comprehensive volumetric imaging of the entire eye and improving diagnostic capabilities in ophthalmology by reducing complex conjugate artifacts and sensitivity falloff.

Implementation Method 1

The longitudinal ranging capability of OCT is generally based on low-coherence interferometry, in which light from a broadband source is split between illuminating the sample of interest and a reference path. The interference pattern of light reflected or backscattered from the sample and light from the reference delay contains information about the location and scattering amplitude of the scatterers in the sample.

Methodology Applied
Scientific EffectInterference: Interference

Implementation Method 2

incorporating techniques like phase modulation and comb filters to enhance imaging depth and reduce artifacts

Methodology Applied
Scientific EffectPhase modulation: Phase Modulation

Data Source

PatentUS9259150B2Systems for comprehensive fourier domain optical coherence tomography (FDOCT) and related methods
Publication Date: 2016.02.16 LEICA MICROSYSTEMS NC INC
  • US9259150B2 patent drawing
  • US9259150B2 patent drawing
  • US9259150B2 patent drawing

AI summary

Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.