Feed Additive Using Hydroxytyrosol Maslinic Acid Oleanolic Acid
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Solution Overview
Problem
Current animal feed additives fail to effectively reduce mortality and improve growth performance in early life stages of livestock, particularly due to antimicrobial resistance concerns and adverse reactions, while also addressing palatability issues that lead to reduced feed intake and weight gain.
Innovation Solution
A combination of hydroxytyrosol (HT), maslinic acid (MA), and oleanolic acid (OA) is used as additives in animal feed at specific concentrations to promote growth, reduce mortality, and enhance intestinal health, stabilizing mastocytes and improving feed intake in young animals.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If antimicrobials and other supplements are administered to reduce mortality and improve growth, then animal health and survival improve, but antibiotic resistance increases and adverse immune reactions occur
Solution Approach 1:
The patent changes the chemical parameters of feed additives by using specific concentrations of hydroxytyrosol (0.01-100 ppm), maslinic acid (1-100 ppm), and oleanolic acid (1-100 ppm). This precise parameter control provides effective protection against intestinal disturbances and pathogens while avoiding the antibiotic resistance issues associated with conventional antimicrobial use.
Solution Approach 2:
The patent combines three different compounds (hydroxytyrosol, maslinic acid, and oleanolic acid) into a composite feed additive formulation. This composite approach provides synergistic effects that enhance animal health and survival while avoiding the harmful effects of single-antimicrobial treatments, including antibiotic resistance development.
2Reliability
If acidifiers and other feed additives are added to protect gastrointestinal health and enhance immune function, then animal health improves, but feed intake is reduced due to aversive taste
Solution Approach 1:
The patent uses extremely low concentrations of active compounds (hydroxytyrosol at 0.01-100 ppm, maslinic acid at 1-100 ppm, oleanolic acid at 1-100 ppm) that are effective for protecting gastrointestinal health but do not produce aversive taste effects. This precise parameter control resolves the contradiction between health protection and feed intake maintenance.
Solution Approach 2:
The patent employs natural compounds from olive extracts that are rapidly metabolized and eliminated from the animal system, providing temporary protective effects without accumulating to levels that would cause taste aversion or other adverse effects.
Data Source
AI summary
Present invention relates to the use of hydroxytyrosol (HT), maslinic acid (MA) and oleanolic acid (OA) as additive in feed for a domesticated animal at very early days of life or from birth. The invention provides an additive with particular amounts of these three ingredients and an additivated feedstuff ready to use comprising said additive.