Female Connector Bag for Needle-Free Pharmaceutical Transfer

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Solution Overview

Problem

Existing methods for storing and transferring pharmaceutical ingredients, such as prefilled syringes, face challenges with sterility, handling risks, and potential for degradation due to oxidation, and require complex and costly production processes.

Innovation Solution

A bag with a female connection system connector system for storing pharmaceutical ingredients, where the bag comprises a female connection part of a male-female tubular connector system, compatible with a male-female tubular connector system, allowing for needle-free transfer to downstream devices.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If needle-free connectors are used, then safety is improved by reducing needle-stick injuries, but compatibility with existing storage containers remains limited

Engineering Contradiction:
Improveneedle-stick injuriesVSAvoidconnector compatibility
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

The patent applies universality by designing a connector system that integrates multiple functions: the female connector on the bag is compatible with both traditional male Luer connectors and male connectors on syringes, allowing the same bag design to work with various downstream devices while maintaining needle-free safety

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Quantity of substance

If larger volumes are stored in pouches, then packaging efficiency is improved, but needle-free transfer compatibility is not achieved

Engineering Contradiction:
Improvestorage volumeVSAvoidneedle-free transfer
Core Design Contradiction:
Quantity of substanceVSEase of operation

Solution Approach 1:

The patent merges two previously separate concepts: the large-volume storage capability of pouches and the needle-free transfer capability of connectors with syringes. By integrating a female connector directly into the pouch body, the invention combines these functions into a single device that maintains both high storage efficiency and safe needle-free operation

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If prefilled syringes are used, then sterility and handling are improved, but production complexity and cost increase

Engineering Contradiction:
ImprovesterilityVSAvoidproduction complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by separating the storage function (bag/pouch) from the administration function (syringe), while maintaining sterility through the needle-free connector interface. This allows independent optimization of each component and simplifies production compared to manufacturing complex prefilled syringes with integrated stoppers and barrels

Inventive Principle:
Principle #1Segmentation

Data Source

PatentEP4670698A1Bag comprising an active pharmaceutical ingredient comprising a female tubular connection part
Publication Date: 2025.12.31 B BRAUN MELSUNGEN AG
  • EP4670698A1 patent drawingFigure 1~2
  • EP4670698A1 patent drawingFigure 3
  • EP4670698A1 patent drawing

AI summary

A bag comprising a liquid comprising a pharmaceutical ingredient, wherein the bag comprises an opening comprising a female connection part of a male-female tubular connector system, wherein the pharmaceutical ingredient is selected from the list consisting of a parenteral nutrition preparation, an electrolyte, and an active pharmaceutical ingredient (API).