Fermented Extract Composition for Skin Improvement

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Solution Overview

Problem

There is a lack of recognition and understanding of the effects on the skin of extracts obtained by stepwise fermentation of koji mold and two types of lactic acid bacteria, particularly the nano-type lactic acid bacteria derived from sunkizuke pickles.

Innovation Solution

A composition for skin improvement is developed using a fermented extract obtained through individual and stepwise fermentation of koji mold (Aspergillus oryzae) and lactic acid bacteria, including a nano-type lactic acid bacterium (Lactbacillus plantarum), which is added after primary and secondary fermentations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a fermented extract is obtained by stepwise fermentation of koji mold and two types of lactic acid bacteria, then the skin improving effects are enhanced (elastase inhibition, collagen production, anti-inflammatory effects), but the manufacturing process complexity increases

Engineering Contradiction:

Improveskin improving effectsVSAvoidmanufacturing process complexity

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The fermentation process is divided into distinct sequential stages: first koji mold fermentation, then first lactic acid bacteria fermentation, and finally second lactic acid bacteria fermentation. Each stage uses a different microorganism to produce specific beneficial compounds, allowing complex skin-improving effects to be achieved through controlled stepwise processing rather than simultaneous fermentation.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The koji mold performs preliminary saccharification of starch into sugars before the lactic acid bacteria can ferment these sugars into lactic acid and other beneficial metabolites. This preliminary action by koji mold creates the necessary substrate for subsequent bacterial fermentation stages, enabling the overall process to produce enhanced skin-improving compounds.

Inventive Principle:

Principle #10Preliminary action

2Reliability

If nano-type lactic acid bacteria (Lactbacillus plantarum) are used in the fermentation process, then the skin improving effects are enhanced, but the difficulty of detecting and measuring the bacteria increases

Engineering Contradiction:

Improveskin improving effectsVSAvoiddetection difficulty

Core Design Contradiction:

ReliabilityVSDifficulty of detecting and measuring

Solution Approach 1:

The lactic acid bacteria are transformed into nano-sized particles through controlled fermentation and extraction processes. This parameter change in size (to nanoscale) enhances their penetration ability and skin-improving effects while requiring specialized detection methods appropriate for nanoscale particles rather than conventional bacterial detection techniques.

Inventive Principle:

Principle #35Parameter changes

3Reliability

If multiple types of microorganisms are used for fermentation, then the beneficial effects on skin are enhanced, but the manufacturing precision requirements increase

Engineering Contradiction:

Improvebeneficial effectsVSAvoidfermentation control precision

Core Design Contradiction:

ReliabilityVSManufacturing precision

Solution Approach 1:

Multiple microorganisms are applied in separate sequential fermentation stages rather than mixed simultaneously. Each stage is optimized for its specific microorganism's requirements, allowing precise control of each fermentation process independently while achieving cumulative beneficial effects from all microorganisms.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

Each microorganism performs a specific preliminary function: koji mold saccharifies starch, first lactic acid bacteria ferment sugars and produce lactic acid, second lactic acid bacteria produce additional metabolites. This preliminary action sequence ensures each microorganism works optimally on substrates prepared by previous stages, reducing manufacturing precision requirements.

Inventive Principle:

Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively inhibits elastase activity, promotes collagen production, and exhibits anti-inflammatory and anti-allergic effects, thereby improving skin functions and preventing skin issues.

Implementation Method 1

adding water to Aspergillus oryzae to perform a primary fermentation for saccharification

Methodology Applied

Scientific EffectFermentation: Fermentation

Implementation Method 2

saccharification

Methodology Applied

Scientific EffectEnzyme: Enzyme

Implementation Method 3

adding a lactic acid bacterium (Lactococcus cremoris H6 strain) to perform a secondary fermentation, and then adding a nano-type lactic acid bacterium (Lactbacillus plantarum)

Methodology Applied

Scientific EffectFermentation: Fermentation

Data Source

PatentUS20250152496A1Skin improving agent containing fermented extract as main raw material

Publication Date: 2025.05.15 AIN HLDG INC

AI summary

Provided is a composition for skin containing, as an active component, an extract obtained by fermentation and aging with koji mold and two types of lactic acid bacteria. As a specific example, an extract obtained by adding water to koji mold (Aspergillus oryzae) to perform a primary fermentation for saccharification, then adding a lactic acid bacterium (Lactococcus cremoris SW01 stain) to perform a secondary fermentation, and then adding a nano-type lactic acid bacterium (Lactbacillus plantarum) is used as an active component.