Bacterially Fermented Hemp Pomace for Cannabinoid Delivery
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Solution Overview
Problem
The existing methods for processing and delivering cannabinoids from hemp often involve extraction with solvents that can alter the chemical composition and lose the synergy of natural compounds, leading to inferior quality products with potential side effects.
Innovation Solution
Bacterially fermented hemp pomace is used as a starting material, containing cannabinoids, dietary fiber, vitamins, and other nutrients, which is then processed into a powdered form and blended with other botanicals or compressed into tablets, retaining live bacteria and moisture to enhance bioavailability and efficacy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If extraction with solvents is used to deliver cannabinoids from hemp, then cannabinoid delivery is achieved, but the chemical composition is altered and synergy of natural compounds is lost
Solution Approach 1:
The patent applies extraction by reversing the conventional approach - instead of using solvents to extract cannabinoids from hemp, the invention uses bacterial fermentation to selectively remove unwanted components (THC, chlorophyll, terpenes) while preserving the desired cannabinoids (CBD, CBG) and their natural matrix. This 'negative extraction' approach maintains chemical composition integrity while achieving cannabinoid delivery.
Solution Approach 2:
The invention utilizes the entire hemp matrix including cannabinoids, dietary fiber, vitamins, and other nutrients as a composite material system. Rather than isolating individual compounds through solvent extraction, the bacterial fermentation process preserves the synergistic composite structure of natural hemp constituents, delivering cannabinoids within their native biochemical environment.
2Quantity of substance
If extraction with solvents is used to obtain cannabinoids, then active agents are isolated, but solvent residues remain and quality is reduced
Solution Approach 1:
The patent converts the harmful effect of traditional solvent extraction into a beneficial process by using bacterial fermentation. Instead of introducing harmful solvents that leave residues, the invention employs beneficial bacteria (Lactobacillus, Bifidobacterium) that naturally metabolize unwanted substances like THC and chlorophyll while producing probiotic benefits, thereby eliminating solvent residue problems entirely.
Solution Approach 2:
Bacteria serve as an intermediary agent between the hemp material and the final cannabinoid product. Rather than using direct chemical solvents, the bacterial fermentation process mediates the transformation of hemp constituents, selectively degrading harmful components while preserving and concentrating desired cannabinoids without leaving any toxic residues.
3Ease of manufacture
If traditional extraction methods are used, then processing is simplified, but the synergy of whole herb compounds is lost
Solution Approach 1:
The bacterial fermentation process performs multiple functions simultaneously: it concentrates desired cannabinoids (CBD, CBG), degrades unwanted substances (THC, chlorophyll, terpenes), produces probiotic benefits, and preserves the synergistic matrix of natural compounds. This multi-functional approach replaces multiple separate processing steps while maintaining compositional integrity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This method increases the ratio of non-hallucinogenic cannabinoids like CBD to THC, reduces side effects, and provides a balanced, whole-food effect with improved delivery and bioavailability of cannabinoids, while avoiding solvent residues and excessive processing.
Implementation Method 1
bacterially fermented spent extracted hemp pomace... Fermentation is conducted with any bacterium suitable for consumption or oral administration, including but not limited to Bacillus subtilis, Bacillus subtilis ssp Natto, Bacillus coagulans, Lactobacillus plantarum
Data Source
AI summary
The present invention is a cannabidiol oral dosage form including predominantly or exclusively bacterially fermented hemp pomace, compounded as a tablet or formulated within a capsule generally without the addition of synthetic excipients, fillers or other additives, not including the inevitable presence of some moisture. The dosage forms contain dietary fiber, important to activity as the desired delivery system, having a ratio of one part soluble dietary fiber to 30 parts insoluble dietary fiber and delivers desirable/non hallucinogenic cannabinoids (CBD, CBG, etc.) in a ratio of 60:1 up to 120:1 to hallucinogenic cannabinoids (THC).