Fermented Mare's Milk Compositions for Immune Support

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Solution Overview

Problem

Current nutritional compositions for domestic animals lack effective solutions for enhancing growth, immune system strengthening, and disease mitigation, particularly in immature mammals, with limited stability and shelf life, and often rely on inconsistent fermentation processes and unknown bacterial/yeast strains.

Innovation Solution

Development of novel nutritional compositions using unique milk fermentation processes with defined bacterial strains, isolating bioactive peptides and components from fermented mare's milk and bovine colostrum, which are stable, easily manufacturable, and provide enhanced nutritional value and immune system support.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional fermentation processes with naturally occurring yeasts and bacteria are used, then the product can be safely preserved over time, but the quality and characteristics vary depending on milk source and fermentation conditions

Engineering Contradiction:
Improveproduct safety and preservationVSAvoidquality consistency
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent applies parameter changes by transitioning from uncontrolled natural fermentation to controlled fermentation with specific parameters: defined bacterial strains (Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus bulgaricus, Streptococcus thermophilus), controlled temperature (37-42°C), controlled pH (4.0-4.5), and defined fermentation time (18-72 hours). This ensures consistent quality while maintaining preservation benefits

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses defined lactic acid bacteria strains as intermediaries to mediate the fermentation process. These specific bacterial strains serve as controlled mediators between the milk substrate and the desired product characteristics, replacing the unpredictable naturally occurring microorganisms while maintaining the fermentation preservation mechanism

Inventive Principle:
Principle #24Intermediary (Mediator)

2Duration of action of stationary object

If fermentation is used to extend shelf life of milk products, then the product can be stored longer, but the continuing action of bacteria and yeast limits shelf life to 10 days at 4°C

Engineering Contradiction:
Improveshelf lifeVSAvoidstorage stability
Core Design Contradiction:
Duration of action of stationary objectVSReliability

Solution Approach 1:

The patent extracts and removes the casein fraction from the fermented milk product. Casein removal serves to stop the continuing bacterial action on protein substrates, thereby extending shelf life beyond the typical 10-day limitation while maintaining the benefits of fermentation. The extracted casein can be separately utilized

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the chemical composition parameters of the fermented product by removing casein, which eliminates the substrate that continues to support bacterial growth during storage. This parameter change (casein removal) stabilizes the product for longer storage while preserving the beneficial effects of fermentation

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If milk with different fat contents is used for fermentation, then diverse food products can be produced, but the product characteristics vary widely and consistency is difficult to achieve

Engineering Contradiction:
Improveproduct varietyVSAvoidquality consistency
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The patent applies parameter changes by controlling the fat content parameter of the milk substrate and the fermentation conditions to produce consistent low-fat fermented milk products. By defining specific parameters (low fat content, defined bacterial strains, controlled temperature and pH), the patent achieves both versatility in product type and consistency in quality

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent applies local quality by creating a standardized fermentation process that can be applied to different milk sources while maintaining consistent product characteristics. The defined bacterial strains and controlled conditions ensure that regardless of the milk source, the final product achieves uniform quality and properties

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compositions effectively promote growth, strengthen the immune system, mitigate infections, and provide long-term health benefits, including anti-anxiety effects and protection against digestive issues, with improved bioavailability of nutrients and extended shelf life without refrigeration.

Implementation Method 1

These processes typically involve adding lactic acid-producing microorganisms, such as bacteria and yeast to milk, which ingest lactose, or milk sugar, and release lactic acid as waste.

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 2

The compositions are prepared by unique milk fermentation processes... isolating bioactive peptides and components from fermented mare's milk and bovine colostrum

Methodology Applied
Scientific EffectEnzymatic hydrolysis: Enzyme

Data Source

PatentUS10772344B2Therapeutic and nutritional compositions
Publication Date: 2020.09.15 INTEQ LLC

AI summary

Novel nutritional compositions and methods for their manufacture, administration and use are disclosed. The nutritional compositions of the present invention are useful for the feeding of immature mammals, particularly those used for food, and/or performance animals, such as horses, and for companion animals, such as dogs and cats. The nutritional compositions and supplements of the present invention are effective in supporting the growth and health of the immature mammal, in supporting and stimulating its immune system, and in mitigating undesirable infections and other. Additionally, particular fractions of the unique peptides produced by the disclosed methods can be separated and utilized as therapeutic agents.