Fermented Milk Starter Composition for Low Post-Acidification

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Solution Overview

Problem

Current methods for producing fermented milk products, such as yoghurt, suffer from post-acidification during storage, leading to reduced shelf life, quality changes, and loss of health benefits due to heat treatment, while existing solutions either inhibit natural sweetness or require complex process adjustments.

Innovation Solution

A composition comprising a starter culture with a glucose-fermenting Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus strains, combined with a glucose-deficient Streptococcus thermophilus strain carrying a mutation in the glcK gene, which reduces post-acidification and enhances natural sweetness.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If rapid cooling is used to terminate fermentation, then post-acidification is prevented, but texture quality is lost

Engineering Contradiction:
Improvecontrol of post-acidificationVSAvoidtexture quality
Core Design Contradiction:
ReliabilityVSShape

Solution Approach 1:

The invention changes the metabolic parameters of the bacterial culture by introducing a glucose-deficient strain, which alters the fermentation dynamics to prevent post-acidification without requiring rapid cooling, thus preserving texture quality

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention extracts the harmful post-acidification effect by removing the ability of certain bacteria to utilize glucose, thereby eliminating the cause of further acidification after the desired pH is reached

Inventive Principle:
Principle #2Taking out (Extraction)

2Duration of action of stationary object

If heat treatment is applied to extend shelf life, then post-acidification is reduced, but health benefits and product quality are diminished

Engineering Contradiction:
Improveshelf lifeVSAvoidhealth benefits and product quality
Core Design Contradiction:
Duration of action of stationary objectVSReliability

Solution Approach 1:

The invention performs preliminary action by selecting and using glucose-deficient bacterial strains from the outset, which prevents post-acidification during storage without requiring subsequent heat treatment, thereby maintaining both shelf life and product quality

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The invention converts the potential harm of continued bacterial activity into a benefit by using glucose-deficient strains that naturally stop producing acid after the desired pH is reached, eliminating the need for heat treatment and preserving health benefits

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Reliability

If acidic pH is used to control post-acidification, then lactic acid production is inhibited, but natural sweetness is reduced

Engineering Contradiction:
Improvecontrol of post-acidificationVSAvoidnatural sweetness
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The invention extracts the glucose utilization capability from certain bacterial strains, which prevents further acidification without requiring high acidic pH, thereby preserving the natural sweetness of the fermented milk product

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Significantly reduces post-acidification, maintains product quality, extends shelf life, and enhances sweetness without heat treatment, benefiting consumers with lactose intolerance.

Implementation Method 1

a milk substrate is fermented by the addition of a starter culture comprising lactic acid bacteria (LAB) capable of metabolizing glucose obtained from lactose present in the milk; during fermentation the LAB metabolizes glucose and produces lactic acid (acidification)

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 2

a glucose-deficient Streptococcus thermophilus (St) strain, wherein said St strain is galactose-fermenting and carries a mutation in the DNA sequence of the glcK gene encoding a glucokinase protein, which mutation inactivates the glucokinase protein or has a negative effect on expression of the gene

Methodology Applied
Scientific EffectGene mutation:

Data Source

PatentUS12564197B2Lactic acid bacteria composition for preparing fermented food products
Publication Date: 2026.03.03 COMPAGNIE GERVAIS DANONE SA

AI summary

The invention relates to a composition for producing a fermented milk product comprising: (i) a starter culture comprising a glucose-fermenting Streptococcus thermophilus (St) strain and a glucose-fermenting Lactobacillus delbrueckii subsp. bulgaricus (Lb) strain; and (ii) a glucose-deficient Streptococcus thermophilus (St) strain, wherein said St strain is galactose-fermenting and carries a mutation in the DNA sequence of the glcK gene encoding a glucokinase protein, which mutation inactivates the glucokinase protein or has a negative effect on expression of the gene.