Fermented Milk Reducing Sympathetic Nerve Activity Index
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Solution Overview
Problem
There is currently no food product that can be easily incorporated into a normal diet to effectively improve autonomic nervous function.
Innovation Solution
Fermented milk containing specific lactic acid bacteria of the genus Lactobacillus, such as Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1, and its metabolites, which significantly reduce the relative sympathetic nerve activity index, thereby improving autonomic nervous function.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional foods are used to improve autonomic nervous function, then the effectiveness is insufficient, but the ease of incorporation into normal diet is compromised
Solution Approach 1:
The patent applies parameter changes by selecting specific Lactobacillus species (L. delbrueckii, L. gasseri, L. rhamnosus, L. acidophilus) and controlling fermentation parameters to produce metabolites with specific biological activities. This targeted approach transforms ordinary fermented milk into a functional product that reliably improves autonomic nervous function while maintaining the familiar form of fermented milk for easy dietary incorporation.
Solution Approach 2:
The patent creates a composite functional product by combining specific Lactobacillus strains with their metabolites in fermented milk. This composite structure integrates the probiotic benefits of live bacteria with the bioactive compounds produced during fermentation, achieving both effectiveness in improving autonomic nervous function and ease of consumption as a familiar food product.
2Reliability
If specific Lactobacillus species and their metabolites are used, then autonomic nervous function improves significantly, but the product complexity increases
Solution Approach 1:
The patent applies universality by using common fermented milk products that serve multiple functions: they provide the familiar dietary vehicle for easy consumption, contain live probiotic bacteria for gut health, and produce bioactive metabolites that specifically target autonomic nervous function improvement. This multi-functionality achieves therapeutic effects without increasing product complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The ingestion of fermented milk with these lactic acid bacteria and their metabolites leads to a remarkable improvement in autonomic nervous function, making it an effective countermeasure against symptoms caused by autonomic nervous system disturbances.
Implementation Method 1
fermented milk prepared using a specific lactic acid bacteria of the genus Lactobacillus and its metabolites
Data Source
AI summary
A fermented milk for improving autonomic nervous function containing at least one lactic acid bacterial species of the genus Lactobacillus and its metabolite. The lactic acid bacterial species of the genus Lactobacillus is selected from the group consisting of Lactobacillus delbrueckii, Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus gasseri, Lactobacillus rhamnosus and Lactobacillus acidophilus. The lactic acid bacterial strain of the genus Lactobacillus is preferably Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1(FERM BP-10741).