Fermented Strain Compositions for Skin Soothing and Wrinkle Reduction

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Solution Overview

Problem

Conventional cosmetic ingredients often cause skin problems such as inflammation, irritation, and lack significant skin improvement effects, while anti-inflammatory agents have safety and stability issues, and moisturizing compositions provide limited benefits.

Innovation Solution

Utilizing strains of Saccharomyces cerevisiae KCTC14779BP, Saccharomyces cerevisiae KCTC14780BP, Lactobacillus fructivorans KCTC14776BP, Bacillus paramycoides KCTC14777BP, and Bacillus megaterium KCTC14778BP for fermented products and fractions thereof in cosmetic, quasi-drug, and food compositions to improve skin conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional cosmetic ingredients (retinoids, adenosine, animal placenta-derived proteins) are used to improve skin wrinkles and elasticity, then skin improvement effects are expected, but skin irritation and safety issues occur

Engineering Contradiction:
Improveskin improvement effectVSAvoidskin irritation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces expensive, potentially harmful conventional cosmetic ingredients (retinoids, adenosine, animal placenta-derived proteins) with a cost-effective alternative: fermented product of a specific Lactobacillus strain. This fermented product achieves comparable or superior skin improvement effects (wrinkle reduction, elasticity enhancement) without the irritation and safety issues associated with conventional ingredients, effectively substituting a 'short-living' fermentation product for stable but harmful conventional additives

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent fundamentally changes the chemical and biological parameters of the cosmetic composition by using a naturally fermented product from Lactobacillus strain instead of synthetic or animal-derived ingredients. This parameter change transforms the composition from potentially irritating conventional ingredients to a biocompatible, naturally derived fermented product that maintains efficacy while improving safety and reducing skin irritation

Inventive Principle:
Principle #35Parameter changes

2Reliability

If conventional anti-inflammatory agents (non-steroids and steroids) are used to reduce inflammation, then inflammation reduction effect is achieved, but safety issues and stability problems occur

Engineering Contradiction:
Improveanti-inflammatory effectVSAvoidcomposition stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent replaces conventional anti-inflammatory agents (non-steroidal anti-inflammatory drugs like ibuprofen and steroid anti-inflammatory drugs like dexamethasone) with a stable, naturally derived alternative: the fermented product of Lactobacillus strain. This fermented product provides sustained anti-inflammatory effects without the stability degradation and safety concerns of conventional pharmaceutical anti-inflammatory agents when used in cosmetic formulations

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The Lactobacillus fermented product acts as an intermediary substance that delivers anti-inflammatory effects without the harsh mechanisms of conventional anti-inflammatory drugs. Instead of directly suppressing inflammation through pharmaceutical action, the fermented product provides gentle, sustained anti-inflammatory benefits through natural metabolic products, bridging the gap between cosmetic safety and therapeutic efficacy

Inventive Principle:
Principle #24Intermediary (Mediator)

3Stability of the object's composition

If existing skincare products are used for skin moisturization, then moisture maintenance is achieved, but significant improvement in skin conditions (wrinkles, elasticity) is not realized

Engineering Contradiction:
Improvemoisture maintenanceVSAvoidskin condition improvement
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent merges multiple skin care functions into a single fermented product from Lactobacillus strain. This fermented product simultaneously provides moisture maintenance, wrinkle improvement, elasticity enhancement, and anti-inflammatory effects, whereas conventional moisturizing products only address hydration without delivering significant anti-aging or skin condition improvement benefits

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The Lactobacillus fermented product exhibits multi-functionality, serving as both a moisturizing agent and an active anti-aging ingredient. It maintains skin hydration while simultaneously improving wrinkles, elasticity, and overall skin condition, making it a universal solution that replaces multiple separate cosmetic products with a single multifunctional fermented preparation

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The strains and their fermented products exhibit excellent skin improvement effects, including wrinkle reduction, elasticity enhancement, skin soothing, and anti-inflammatory properties, surpassing conventional yeast and Bacillus products.

Implementation Method 1

a method for preparing a fermented product, including: fermenting with a strain selected from the group consisting of Saccharomyces cerevisiae deposited under Accession No. KCTC14779BP, Saccharomyces cerevisiae deposited under Accession No. KCTC14780BP, Lactobacillus fructivorans deposited under Accession No. KCTC14776BP

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS12611372B2Strain and use thereof
Publication Date: 2026.04.28 LG HOUSEHOLD & HEALTH CARE LTD
  • US12611372B2 patent drawing

AI summary

Methods are disclosed for preparing a fermentation product of a strain selected from the group consisting of Saccharomyces cerevisiae KCTC14779BP, Saccharomyces cerevisiae KCTC14780BP, Lactobacillus fructivorans KCTC14776BP, Bacillus paramycoides KCTC14777BP, and Bacillus megaterium KCTC14778BP. A cosmetic composition, a quasi-drug composition, or a food composition comprising any one or more of these strains, a culture of the strain, a fermented product of the strain, and a fraction of the culture or fermented product are also described, which may have excellent effects of improving skin and soothing sensitive skin.