Pre-Post FFR Measurement for Blood Flow Assessment
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Solution Overview
Problem
Current methods for assessing the effectiveness of cardiovascular procedures, such as stent placement, do not provide a clear measure of the degree of post-therapy improvement in blood flow, leaving uncertainty about the success of the treatment.
Innovation Solution
A system that compares pre-therapy and post-therapy physiological measurements, such as fractional flow reserve (FFR), to determine the degree of improvement in blood flow, using a combination guidewire with pressure and flow measuring capabilities, and customizable displays to present the results.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If FFR measurement is performed before and after therapy to assess treatment effectiveness, then the ability to evaluate procedural success is improved, but the complexity of the measurement system increases
Solution Approach 1:
The system performs a pre-therapy FFR measurement before the cardiovascular procedure to establish a baseline. This preliminary measurement allows for comparison with post-therapy results, enabling assessment of treatment effectiveness without requiring complex additional equipment during the procedure itself.
Solution Approach 2:
The system measures FFR after therapy and compares it with the pre-therapy baseline measurement. This feedback mechanism provides quantitative information about the degree of improvement, allowing physicians to objectively evaluate whether the treatment achieved the desired therapeutic effect.
2Loss of information
If multiple physiological measurements are taken and compared to determine functional gain, then the information completeness is improved, but the time required for assessment increases
Solution Approach 1:
The pre-therapy FFR measurement establishes a baseline that is stored and used for later comparison. This preliminary data collection eliminates the need to perform all measurements simultaneously, allowing for efficient post-therapy assessment by simply comparing the new measurement against the stored baseline.
Solution Approach 2:
The same FFR measurement system and methodology are used for both pre-therapy and post-therapy assessments. This universal approach allows consistent data collection that can be directly compared, providing complete functional gain information through a standardized process that minimizes additional time requirements.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables physicians to accurately assess and document the degree of post-therapy improvement, providing a quantitative measure of treatment effectiveness and patient progress.
Implementation Method 1
Distal coronary pressure is usually measured with a pressure sensor mounted on the distal portion of a guidewire
Data Source
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AI summary
The present invention generally relates to methods for determining the degree of improvement after a therapeutic procedure. The method can involve determining a baseline measurement prior to conducting a therapeutic procedure, conducting the therapeutic procedure, and determining a post-therapy measurement after conducting the therapeutic procedure. The method further involves comparing the post-therapy measurement to the baseline measurement, thereby determining the degree of improvement after conducting the therapeutic procedure.