Fiber Optic Sensor for Bilirubin Monitoring

The patent uses an optical fiber as an intermediary medium to transmit light through the skin to measure bilirubin levels. The optical fiber enables indirect measurement by guiding light through tissue and detecting the reflected/absorbed light, thus achieving non-invasive measurement while maintaining accuracy comparable to blood tests.

The patent replaces mechanical/invasive blood sampling methods with an optical-based measurement system. By using light interaction with chromophoric compounds in tissue, the system eliminates the need for needle sticks while providing accurate real-time bilirubin monitoring.

The patent enables continuous monitoring of bilirubin levels by maintaining constant optical contact with the tissue through the optical fiber. This allows real-time measurement without repeated invasive blood draws, providing continuous data streams that reflect current bilirubin levels immediately.

The optical fiber serves as a mediator that allows repeated measurements without repeated skin penetration. Once the fiber is in place, it can continuously measure bilirubin levels through optical interaction with tissue, eliminating the need for repeated invasive procedures.

The patent implements a feedback mechanism by continuously monitoring theophylline levels in real-time and using this information to adjust infusion rates. When levels approach toxic thresholds, the system alerts clinicians to reduce infusion, preventing toxicity while maintaining therapeutic effectiveness through dynamic adjustment.

The patent enables preliminary detection of rising theophylline levels before toxicity occurs. By continuously monitoring and providing early warning of approaching toxic thresholds, the system allows preventive action to be taken before harmful effects manifest, balancing therapy with safety.