Fiber Optic Dosimeter Probe for MR-Guided Radiotherapy

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Solution Overview

Problem

Current dosimeters used in radiotherapy for monitoring radiation dose delivery are complex, expensive, and introduce errors due to non-tissue equivalence and metallic components that alter dose distribution, particularly in MR-guided radiotherapy and brachytherapy.

Innovation Solution

A fiber optic dosimeter probe with a radiation-sensitive layer made of radiochromic material, integrated with an optical fiber and a reflector, providing a water-equivalent and MR-compatible solution for real-time dose monitoring, using a biocompatible sheath and adhesive to minimize interaction with radiation and maintain geometric integrity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If current commercially available dosimeters (TLDs, MOSFETs, ion-chambers, scintillators) are used for radiation dose monitoring, then dose measurement capability is achieved, but device complexity, cost, and metallic component interference with radiation field increase

Engineering Contradiction:
Improvedose measurement accuracyVSAvoidinstrumentation complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts and removes metallic components from the dosimeter structure, using only non-metallic, MR-compatible materials (optical fiber, radiochromic film, polymer encapsulation) to eliminate the harmful interaction with radiation fields while maintaining dosimetry functionality

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces electronic readout mechanisms (MOSFETs, ion-chambers, scintillators) with an optical-based system using radiochromic film that changes optical properties upon radiation exposure, eliminating complex electronics and metallic components

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If dosimeters with metallic components are used, then dose measurement is enabled, but dose distribution accuracy deteriorates due to non-tissue equivalence and perturbation of radiation field

Engineering Contradiction:
Improvedose measurement capabilityVSAvoidradiation field perturbation
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent uses homogeneous non-metallic materials (polymer encapsulation, optical fiber, radiochromic film) that are tissue-equivalent and do not perturb the radiation field, matching the physical and radiological properties of surrounding tissue

Inventive Principle:
Principle #33Homogeneity

Solution Approach 2:

The patent employs composite material structure combining optical fiber, radiochromic film, and polymer encapsulation to achieve both dosimetry functionality and tissue-equivalence without metallic components

Inventive Principle:
Principle #40Composite materials

3Measurement precision

If MR-compatible dosimeters are required for MR-guided radiotherapy, then geometric integrity and localization accuracy are improved, but device selection and implementation complexity increase

Engineering Contradiction:
Improvelocalization accuracyVSAvoidMR-compatibility requirements
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent removes all ferromagnetic and MR-incompatible materials from the dosimeter construction, using only non-metallic components that are inherently MR-compatible and maintain geometric integrity during MRI scanning

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent creates a universal dosimeter design that simultaneously achieves dosimetry, MR-compatibility, and real-time optical readout capabilities, applicable to both MR-guided radiotherapy and brachytherapy without modification

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The fiber optic dosimeter probe offers accurate, real-time radiation dose monitoring with minimal perturbation of the local field, maintaining geometric integrity and allowing for precise localization, reducing errors and costs associated with existing technologies.

Implementation Method 1

A radiation sensitive layer is provided between the sensitive end and a window. The radiation sensitive layer is made of a material which has an optical property that changes with absorbed radiation dose

Methodology Applied
Scientific EffectRadiochromism: Photochromism

Implementation Method 2

an optical fiber having a free end and a sensitive end

Methodology Applied
Scientific EffectOptical fiber transmission: Optical Fibre

Implementation Method 3

A reflector is provided on a reflector side of the radiation sensitive layer. The reflector side is opposed to the fiber side

Methodology Applied
Scientific EffectLight reflection: Reflection

Data Source

PatentUS9000401B2Fiber optic radiochromic dosimeter probe and method to make the same
Publication Date: 2015.04.07 INSTITUT NATIONAL D'OPTIQUE
  • US9000401B2 patent drawing
  • US9000401B2 patent drawing
  • US9000401B2 patent drawing

AI summary

A fiber optic dosimeter probe for sensing radiation dose including an optical fiber having a free end and a sensitive end, a window having a sensitive side and a rear side; a radiation sensitive layer between the sensitive end of the optical fiber and a sensitive side of the window, the radiation sensitive layer being made of a material having an optical property that changes with absorbed radiation dose, an amount of the material corresponding to a predetermined sensitivity to radiation; wherein the window and the optical fiber have a near water equivalent interaction with radiation and are MR compatible.