Fibrin Compression Container for Stable Tissue Fixation

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Solution Overview

Problem

Existing methods for obtaining Platelet Rich Fibrin (PRF) using glass-coated tubes are inadequate for hard tissue healing due to limited exposure duration and potential harmful effects of silica particles, and PRF fixation in both soft and hard tissues is challenging due to lack of resistance and deformation issues.

Innovation Solution

A fibrin compression container and apparatus with a network structure that uses calcium phosphate compounds and biocompatible materials to enhance fibrin formation and fixation, allowing for three-dimensional healing by incorporating stem cells and bioactive agents between layers, facilitating stable fibrin structure and surface adaptation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If glass-coated tubes are used to obtain Platelet Rich Fibrin, then fibrin formation is achieved, but the exposure duration is limited and silica particles may have harmful effects

Engineering Contradiction:
Improvefibrin formation stabilityVSAvoidsilica particle harm
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The invention removes the glass coating from the tube surface, extracting the harmful silica particles from the system while retaining the tube's basic function of containing blood for centrifugation. This eliminates the source of harmful silica particle exposure to tissues.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention employs disposable plastic tubes without glass coating, replacing durable but harmful glass-coated tubes. These disposable tubes achieve the necessary fibrin formation function without introducing harmful silica particles, and are discarded after single use to prevent contamination.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Quantity of substance

If traditional PRF methods are used, then platelet rich fibrin is obtained, but fixation to soft and hard tissues is challenging due to lack of resistance and deformation

Engineering Contradiction:
Improvefibrin quantityVSAvoidtissue fixation strength
Core Design Contradiction:
Quantity of substanceVSStrength

Solution Approach 1:

The invention creates a composite structure by combining platelet-rich fibrin with a biocompatible mesh or scaffold material. This composite provides both the biological activity of PRF and the mechanical strength needed for stable fixation to soft and hard tissues, preventing deformation while maintaining fibrin quantity.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The invention uses porous mesh or scaffold structures as a support framework for the fibrin. These porous materials allow fibrin infiltration while providing mechanical resistance and structural integrity, enabling stable fixation to tissues without causing deformation of the fibrin mass.

Inventive Principle:
Principle #31Porous materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables stable and long-lasting fibrin formation, improved wound healing, and enhanced tissue integration by providing a biocompatible and shapeable fibrin matrix that can be easily fixed to both soft and hard tissues, accelerating the healing process and improving implant osseointegration.

Implementation Method 1

Calcium phosphate compounds and autogenous or non-autogenous graft materials, bone morphogenic proteins, growth factors, bioactive agents such as PDGF, stem cells, puliripotent cells and fibrin or collagen obtained from a patient himself that accelerate fibrin formation

Methodology Applied
Scientific EffectCoagulation: Coagulation

Implementation Method 2

Through the fibrin generation apparatus (1) inserted into the tube, shapeable fibrin is formed on the network structured apparatus

Methodology Applied
Scientific EffectCentrifugal separation: Centrifugal Separation

Data Source

PatentUS10213489B2Three dimensional healing kit
Publication Date: 2019.02.26 AKMAN SERHAN
  • US10213489B2 patent drawing
  • US10213489B2 patent drawing
  • US10213489B2 patent drawing

AI summary

Invention; is about the kit that enables three-dimensional healing with the platelet-rich fibrin framework support used in hard and soft tissue healing.