Uterine Fibroid Ablation via MRI-Guided Radiofrequency Electrode

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Solution Overview

Problem

Current methods for uterine fibroid ablation are invasive, require specialized skills and equipment, and are often inaccessible due to high costs and limited availability of trained professionals, leading to incomplete removal and potential damage to surrounding tissues.

Innovation Solution

A system integrating an ultrasound scanner with a controllable energy source and a device featuring an electrode for precise ablation, guided by real-time imaging and navigation parameters, allowing for minimally invasive procedures that can be performed in a limited resource setting without the need for highly skilled surgeons.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If surgical removal of fibroids is performed, then complete removal of fibroids is achieved, but morbidity increases and recovery time lengthens

Engineering Contradiction:
Improvecomplete removal of fibroidsVSAvoidmorbidity and recovery time
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces mechanical surgical removal with thermal ablation using radiofrequency energy. The electrode delivers thermal energy to destroy fibroid tissue in place, eliminating the need for mechanical excision and associated surgical trauma, thereby reducing morbidity and recovery time while achieving complete fibroid destruction

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces real-time MRI imaging as an intermediary to guide the ablation process. The MRI scanner provides continuous feedback on electrode position and tissue temperature, enabling precise control of the ablation zone to ensure complete fibroid destruction while protecting surrounding healthy tissues

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If MRgFUS is used for ablation, then non-invasive procedure is achieved, but equipment cost and operational complexity increase

Engineering Contradiction:
ImproveinvasivenessVSAvoidequipment and skill requirements
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent uses real-time MRI imaging as an intermediary guidance system that integrates with the ablation device. The MRI scanner provides continuous feedback on electrode position and tissue temperature, enabling precise control of the ablation zone without requiring complex specialized equipment or highly trained personnel

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent implements real-time feedback through MRI imaging during the ablation procedure. The system continuously monitors temperature distribution and fibroid tissue changes, automatically adjusting treatment parameters to achieve complete ablation while minimizing damage to surrounding tissues, thereby simplifying the procedure and reducing the need for highly specialized operators

Inventive Principle:
Principle #23Feedback

3Object-affected harmful factors

If RF ablation with ultrasound guidance is used, then minimally invasive approach is achieved, but incomplete removal and damage to surrounding organs occur

Engineering Contradiction:
ImproveinvasivenessVSAvoidcomplete removal and safety
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent replaces ultrasound imaging with real-time MRI imaging for guidance during RF ablation. MRI provides superior soft tissue contrast and multi-planar visualization, enabling precise tracking of the electrode tip and real-time monitoring of the ablation zone expansion, thereby ensuring complete fibroid destruction while protecting surrounding healthy organs

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements real-time feedback through MRI imaging that continuously monitors the ablation process. The system tracks temperature distribution and fibroid tissue changes, automatically adjusting treatment parameters to achieve complete ablation while minimizing damage to surrounding tissues, thereby improving both completeness of removal and safety

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables safe, cost-effective, and clinically effective uterine fibroid ablation with reduced recovery time and minimal risk to surrounding tissues, accessible in a variety of settings, including outside an operating theater.

Implementation Method 1

a controllable energy source coupled with the electrode and configured to supply energy to the electrode

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 2

enabling the electrode to ablate the fibroid

Methodology Applied
Scientific EffectAblation: Ablation

Implementation Method 3

an ultrasound scanner configured to perform a volume scan of a uterus of a patient

Methodology Applied
Scientific EffectUltrasound: Ultrasound

Data Source

PatentUS12053235B2System and method for the ablation of uterine fibroids
Publication Date: 2024.08.06 NESA MEDTECH
  • US12053235B2 patent drawing
  • US12053235B2 patent drawing
  • US12053235B2 patent drawing

AI summary

The present disclosure provides a system for ablation of uterine fibroid(s), said system comprising: an ultrasound scanner configured to perform a volume scan of a uterus of a patient; a display coupled with the ultrasound scanner, configured for displaying image and alphanumeric characters; a device comprising an electrode for ablating the uterine fibroid; a controllable energy source coupled with the electrode and configured to supply energy to the electrode. The system comprises one or more processors configured to: receive ultrasound image data from the ultrasound scanner; process the image data to generate a three-dimensional representation of the uterus of the patient; determine location and size of one or more fibroids in the uterus; determine one or more navigation parameters for the electrode, from the display; determine ablation parameters required by the electrode to ablate the fibroid, wherein the device is operatively coupled to the one or more processors, said one or more processors configured to guide the electrode to a required point in the fibroid based on the determined one or more navigation parameters on the display, and wherein, on receipt of a signal, the controllable energy source supplies power to electrode to enable ablation of the fibroid.