Ficus Serum Fraction Extraction for Skin Hyperpigmentation

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Solution Overview

Problem

Current skin lightening products often use harsh chemical solvents for extraction, leading to incomplete bioactivity spectrum, skin irritation, and environmental harm, while demanding natural and sustainable solutions for hyperpigmentation.

Innovation Solution

The development of Ficus serum fraction derived from fresh Ficus leaf cell juice, processed without solvents to maintain bioactivity and ecological sustainability, which is applied topically to disrupt melanin synthesis and reduce hyperpigmentation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If harsh chemical solvents are used for extraction, then extraction efficiency is improved, but skin irritation and environmental harm worsen

Engineering Contradiction:
Improveextraction efficiencyVSAvoidskin irritation
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the extraction parameter from harsh chemical solvents to water-based extraction methods. This parameter change maintains extraction efficiency while eliminating skin irritation and environmental harm associated with chemical solvents, directly resolving the technical contradiction between productivity and harmful factors.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses water as the extraction medium instead of expensive and harmful chemical solvents. Water is inexpensive, environmentally benign, and safe for skin contact, allowing efficient extraction without the harmful side effects of traditional solvents.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Productivity

If harsh chemical solvents are used for extraction, then extraction efficiency is improved, but environmental harm worsens

Engineering Contradiction:
Improveextraction efficiencyVSAvoidenvironmental harm
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The extraction method parameter is changed from chemical solvents to water-based extraction. This maintains the ability to extract bioactive compounds efficiently while eliminating the environmental contamination and ecological damage caused by harsh chemical solvents.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent converts the traditionally harmful role of solvents into a beneficial process by using water - the most benign solvent available. This transforms the extraction process from an environmentally harmful operation to an eco-friendly procedure that maintains high extraction efficiency.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Ease of manufacture

If traditional extraction methods are used, then manufacturing simplicity is maintained, but bioactivity spectrum completeness worsens

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidbioactivity spectrum
Core Design Contradiction:
Ease of manufactureVSQuantity of substance

Solution Approach 1:

The patent changes the extraction parameter from solvent-based to water-based extraction, which preserves a broader spectrum of bioactive compounds including heat-sensitive and solvent-sensitive compounds. This parameter change maintains manufacturing simplicity while significantly improving the completeness of the bioactivity spectrum.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The Ficus serum fraction effectively inhibits melanin production, providing superior skin lightening effects with enhanced bioactivity and safety, while being environmentally friendly and sustainable.

Implementation Method 1

Tyrosinase catalyzes the conversion of L-tyrosine to DOPA (L-3,4-dihydroxyphenylalanine) and of DOPA to dopaquinone. Dopaquinone undergoes further conversion to form melanin.

Methodology Applied
Scientific EffectEnzyme inhibition: Enzyme

Data Source

PatentUS11766397B2Bioactive compositions comprising <i>ficus </i>serum fracton and methods to reduce the appearance of skin hyperpigmentation
Publication Date: 2023.09.26 ISP INVESTMENTS LLC
  • US11766397B2 patent drawing
  • US11766397B2 patent drawing
  • US11766397B2 patent drawing

AI summary

The present invention provides bioactive compositions comprising Ficus serum fraction derived from Ficus cell juice of fresh Ficus leaves and a process of preparing the Ficus serum fraction. The compositions have biological activity capable of reducing skin hyperpigmentation.