Fiducial Marker Co-Registration of Intravascular and Extravascular Data

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Solution Overview

Problem

Existing imaging technologies struggle to integrate and co-register intravascular and extravascular data effectively, limiting the accuracy and efficiency of vascular clinical procedures.

Innovation Solution

A method and system for registering intravascular data with extravascular data, such as angiography and optical coherence tomography, by superimposing features and locations in real-time, using machine learning models and fiducial markers to enhance accuracy and reduce the need for contrast agents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If intravascular and extravascular data are integrated and co-registered in real-time, then the accuracy of vascular procedures is improved, but the device complexity and processing requirements increase

Engineering Contradiction:

Improveaccuracy of vascular proceduresVSAvoiddevice complexity

Core Design Contradiction:

Measurement precisionVSDevice complexity

Solution Approach 1:

The patent uses fiducial markers as intermediary objects that appear in both intravascular and extravascular imaging modalities. These markers serve as reference points that enable co-registration between the two different imaging systems, bridging the gap between intravascular (e.g., OCT, IVUS) and extravascular (e.g., angiography, CT) data without requiring complex direct transformation algorithms

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a virtual copy or model of the vascular anatomy by integrating intravascular imaging data with extravascular angiography data. This registered model allows operators to visualize and plan procedures using the combined information, improving accuracy without requiring simultaneous operation of all imaging systems

Inventive Principle:

Principle #26Copying

2Productivity

If real-time integration of intravascular and extravascular data is implemented, then procedure efficiency is improved, but the processing time and computational resources increase

Engineering Contradiction:

Improveprocedure efficiencyVSAvoidprocessing time

Core Design Contradiction:

ProductivityVSLoss of time

Solution Approach 1:

The patent performs data pre-processing and feature extraction before the actual co-registration process. By preparing the data in advance and identifying key features (such as fiducial marker locations, vessel contours) beforehand, the system reduces the computational burden during real-time integration, allowing faster processing without sacrificing accuracy

Inventive Principle:

Principle #10Preliminary action

3Loss of information

If multiple imaging modalities are combined, then the information completeness is improved, but the difficulty of detecting and measuring features increases

Engineering Contradiction:

Improveinformation completenessVSAvoiddifficulty of detecting and measuring features

Core Design Contradiction:

Loss of informationVSDifficulty of detecting and measuring

Solution Approach 1:

The patent employs fiducial markers that are universally detectable across multiple imaging modalities. These markers can be visualized in both intravascular (OCT, IVUS) and extravascular (angiography, fluoroscopy) imaging systems, providing a common reference framework that simplifies feature detection and measurement across different data types

Inventive Principle:

Principle #6Universality (Multi-functionality)

Data Source

PatentUS20250318880A1Systems and methods for registering intravascular and extravascular data

Publication Date: 2025.10.16 KONINKLIJKE PHILIPS NV

AI summary

Provided herein are systems and methods for registering extravascular and intravascular data.