Fine Needle-Like Taurine Crystals for Smooth Skin Application

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Solution Overview

Problem

Conventional methods for producing taurine crystals do not control the size and shape effectively, leading to a rough feel when applied in skin external agents, affecting the user experience.

Innovation Solution

A method involving the controlled crystallization of taurine by mixing an aqueous solution with a liquid substance having low solubility, allowing recrystallization to form fine needle-like or columnar crystals with specific dimensions, typically less than 150 micrometers thick and 3000 micrometers long.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional crystallization methods are used to obtain taurine crystals, then high purity and high yield are achieved, but the crystal size and shape cannot be controlled, resulting in a rough feeling when applied to skin

Engineering Contradiction:
Improvecrystal size controlVSAvoiduse feeling
Core Design Contradiction:
Manufacturing precisionVSEase of operation

Solution Approach 1:

The patent applies parameter changes by controlling crystallization conditions including temperature (cooling from elevated temperature to room temperature or lower), solvent composition (using alcohol aqueous solutions with specific alcohol content), and concentration to produce fine needle-like or columnar crystals with controlled size (0.1-10 μm diameter, 1-100 μm length) that provide smooth use feeling while maintaining high purity and yield

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent utilizes phase transitions during crystallization by cooling the taurine solution from elevated temperature to room temperature or lower, inducing controlled phase change from dissolved state to crystalline state, forming fine needle-like or columnar crystals with specific morphology that eliminate rough use feeling while achieving high purity and yield

Inventive Principle:
Principle #36Phase transitions

2Stability of the object's composition

If large taurine crystals are used in skin external agents, then the crystal form is stable, but the application feel becomes rough and uncomfortable

Engineering Contradiction:
Improvecrystal form stabilityVSAvoidapplication feel
Core Design Contradiction:
Stability of the object's compositionVSEase of operation

Solution Approach 1:

The patent changes physical parameters of the crystals by controlling crystallization temperature, solvent composition, and cooling rate to produce fine needle-like or columnar crystals with dimensions of 0.1-10 μm diameter and 1-100 μm length, maintaining compositional stability while achieving smooth application feel without roughness

Inventive Principle:
Principle #35Parameter changes

3Reliability

If fine needle-like crystals of taurine are formed, then skin permeability is improved and pharmacological effect is enhanced, but the crystal production becomes more difficult to control

Engineering Contradiction:
Improveskin permeabilityVSAvoidcrystallization process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent simplifies the crystallization process by using straightforward parameter changes: dissolving taurine in alcohol aqueous solution, heating to elevated temperature, cooling to room temperature or lower, and filtering. This simple process reliably produces fine needle-like or columnar crystals with controlled size that enhance skin permeability and pharmacological effect without requiring complex equipment or procedures

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The controlled crystal shape improves the skin permeability of taurine, enhancing its pharmacological effect while providing a smooth application feel without roughness.

Implementation Method 1

creating an extremely low solubility state by either adding an aqueous solution in which taurine is dissolved to a liquid substance having a low solubility of taurine or gently pouring a liquid substance having a low solubility of taurine into an aqueous solution in which taurine is dissolved to form an interface, and then proceeding recrystallization

Methodology Applied
Scientific EffectRecrystallization: Crystallisation

Data Source

PatentUS20250205185A1Skin external agent composition in which fine needle-like or columnar crystals of taurine are blended
Publication Date: 2025.06.26 COSMED PHARMA
  • US20250205185A1 patent drawing
  • US20250205185A1 patent drawing

AI summary

Provided is a skin external agent composition containing taurine as crystals, which has smooth feel without any skin contact. A skin external agent composition containing fine needle-like or columnar crystals of taurine having a thickness of less than 150 micrometers and a length of less than 3000 micrometers, a method for producing fine needle-like or columnar crystals of taurine, the method including a step of growing crystals in an environment in which an aqueous solution in which taurine is dissolved is mixed with or brought into contact with a liquid substance having low solubility of taurine, and a method for producing a skin external agent composition, the method including the step of growing crystals and a step of blending the fine needle-like or columnar crystals of taurine obtained in the step of growing crystals into the skin external agent composition.