Fipronil Gel Viscosity Plastic Migration

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Solution Overview

Problem

Fipronil gel formulations experience stability issues and migration when packaged in plastics, leading to reduced efficacy and shelf life, as they tend to leach into plastic materials during storage.

Innovation Solution

A fipronil emulsion composition is developed with specific concentrations of fipronil, arthropod attractants, surfactants, gelling agents, preservatives, and solvents, formulated to maintain a viscosity of over 50 centipoises, which when stored in plastic packaging retains more than 90% of fipronil for three months at 25°C, utilizing surfactants like polyoxyethylene (20) sorbitan monopalmitate and ethoxylated hydrogenated castor oil to prevent migration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If fipronil gel formulations are packaged in plastic materials, then packaging cost and versatility are improved, but fipronil migrates to the plastics during storage, reducing product stability and efficacy

Engineering Contradiction:
Improvepackaging cost and versatilityVSAvoidfipronil stability
Core Design Contradiction:
Ease of manufactureVSStability of the object's composition

Solution Approach 1:

The patent introduces an intermediary substance (aromatic compound) that acts as a barrier between fipronil and the plastic packaging material. This mediator prevents direct interaction and migration of fipronil to the plastic, while allowing the formulation to remain in cost-effective plastic packaging rather than requiring expensive glass containers.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent modifies the chemical composition parameters of the gel formulation by adding specific aromatic compounds (such as vanillin, eugenol, or cinnamaldehyde) at controlled concentrations. This parameter change alters the formulation's interaction with plastic materials, preventing fipronil migration while maintaining product efficacy.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If fipronil gel formulations are stored in plastic packaging, then packaging versatility is improved, but shelf life is reduced due to fipronil migration and degradation

Engineering Contradiction:
Improvepackaging versatilityVSAvoidshelf life
Core Design Contradiction:
Adaptability or versatilityVSDuration of action of stationary object

Solution Approach 1:

The aromatic compound serves as a protective intermediary that remains stable during storage and prevents fipronil from interacting with and migrating to the plastic packaging material, thereby extending the product's shelf life while maintaining the advantages of plastic packaging versatility.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent applies preliminary protection by incorporating the aromatic compound into the formulation before packaging. This pre-established protective mechanism prevents fipronil migration during the entire storage period, ensuring product stability throughout the extended shelf life without requiring special packaging conditions.

Inventive Principle:
Principle #10Preliminary action

3Device complexity

If conventional gel formulations are used, then simplicity of formulation is maintained, but fipronil retention in plastic packaging is reduced due to migration

Engineering Contradiction:
Improveformulation simplicityVSAvoidfipronil retention
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent makes a minimal parameter change to the conventional formulation by adding aromatic compounds at specific concentrations (e.g., 0.01-5% w/w). This small compositional modification dramatically improves fipronil retention in plastic packaging while maintaining the overall simplicity and ease of manufacture of the gel formulation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite gel formulation that combines fipronil with aromatic compounds (such as vanillin, eugenol, or cinnamaldehyde). This composite material exhibits improved compatibility with plastic packaging materials, preventing fipronil migration while maintaining the desired gel properties and simplicity of application.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation significantly enhances the stability and retention of fipronil in plastic packaging, maintaining over 90% of its content for three months, effectively preventing migration and ensuring prolonged shelf life and efficacy.

Implementation Method 1

The composition contains polyoxythylene (2) sorbitan monopalmitate, ethoxylated hydrogenated castor oil, glycereth-17 cocoate, and a combination thereof as the surfactant

Methodology Applied
Scientific EffectSurfactant: Surfactant

Implementation Method 2

at least one gelling agent in an amount from about 0.1 wt. % to 5 wt. %. The insecticidal composition is provided in a form of an emulsion that has a viscosity of more than about 50 centipoises

Methodology Applied
Scientific EffectGel: Gel

Data Source

PatentUS20240206467A1Fipronil Containing Insecticide Gels
Publication Date: 2024.06.27 HENKEL KGAA

AI summary

An insecticidal composition includes fipronil in an amount of less than 0.1 wt. %, at least one surfactant, at least one emulsion stabilizer, and at least one arthropod attractant, wherein the insecticidal composition has a viscosity of more than about 50 centipoises. The insecticidal composition has improved stability and prevents migration of fipronil into plastic packaging over time, such that the composition retains more than about 90% of fipronil when stored in a plastic packaging for 3 months or more at room temperature.