Fish Ectoparasite Treatment With Neonicotinoid Water Exchange

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

There is a need for a commercially-viable treatment for ectoparasites in fish that addresses safety, environmental, and treatment-resistance issues, particularly for ectoparasites such as sea lice, which are challenging to treat effectively in a non-laboratory, commercial environment using neonicotinoids without causing environmental harm and promoting resistance.

Innovation Solution

A neonicotinoid is administered to fish at concentrations ranging from 1 to 500 ppm, with the treated water being exchanged to separate the ectoparasites from the fish, ensuring the ectoparasites are induced to detach without being killed initially, and collected to prevent environmental release, using a composition that may include imidacloprid, clothianidin, or other neonicotinoids.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If neonicotinoids are used to treat ectoparasites in fish, then treatment effectiveness is improved, but environmental harm and resistance development worsen

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidenvironmental harm
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and removes the treated water containing dead ectoparasites from the fish treatment system. By separating the contaminated water from the fish and environment, the harmful effects are contained and prevented from spreading, while the treatment effectiveness is maintained through proper disposal of the extracted waste.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent discards the treated water containing dead ectoparasites through controlled drainage or pumping systems. This prevents the accumulation and potential environmental release of harmful substances, while maintaining treatment effectiveness by ensuring continuous water exchange in the treatment system.

Inventive Principle:
Principle #34Discarding and recovering

2Reliability

If neonicotinoids are used to treat ectoparasites in fish, then treatment effectiveness is improved, but ectoparasite resistance worsens

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidectoparasite resistance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent employs combinations of different neonicotinoid compounds (imidacloprid, clothianidin, thiacloprid) at varying concentrations and exposure times. By changing the parameters of treatment (compound selection, concentration, duration), the system maintains effectiveness against resistant ectoparasite populations while minimizing resistance development.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If water immersion treatment is used, then treatment simplicity is improved, but environmental release of chemicals worsens

Engineering Contradiction:
Improvetreatment simplicityVSAvoidchemical release
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent introduces controlled water exchange systems as an intermediary mechanism between the treatment chamber and the environment. Treated water is pumped out and replaced with fresh water, acting as a controlled intermediary process that maintains treatment simplicity while preventing uncontrolled environmental release of chemicals.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Reliability

If ectoparasites are killed in treatment water, then treatment effectiveness is improved, but risk of environmental release worsens

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidrisk of environmental release
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent extracts and removes the treatment water containing dead ectoparasites from the system through controlled drainage or pumping. This extraction process separates the harmful waste from the fish and environment, preventing environmental release while maintaining treatment effectiveness through proper waste management.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively removes ectoparasites like sea lice from fish, minimizing environmental impact and resistance development, while ensuring the fish are not contaminated with dead ectoparasites, thus maintaining a safe and effective treatment process.

Implementation Method 1

administering to the fish an agonist or antagonist of nicotinergic acetylcholine receptors

Methodology Applied
Scientific EffectReceptor binding:

Implementation Method 2

the water comprising the removed ectoparasites is exchanged with replacement water, thereby separating the removed ectoparasites and the fish

Methodology Applied
Scientific EffectFluid displacement:

Data Source

PatentEP4186366B1Treatment for removing ectoparasites from fish
Publication Date: 2025.10.08 BENCHMARK ANIMAL HEALTH
  • EP4186366B1 patent drawingFigure 1
  • EP4186366B1 patent drawingFigure 2

AI summary

A method for removing ectoparasites from a fish in water may comprise administering to the fish a neonicotinoid to remove the ectoparasites from the fish and exchanging the water comprising the neonicotinoid and the removed ectoparasites with replacement water, thereby separating the removed ectoparasites and the fish. The method may comprise the further step of preventing release of the removed ectoparasites into the environment, for example by passing sample of the water comprising the removed ectoparasite through a mesh filter. A neonicotinoid may be used in treating an ectoparasite infestation in a fish, and a composition for use in treating an ectoparasite infestation in a fish may comprise one or more ectoparasiticides, wherein one of the one or more ectoparasiticides is the neonicotinoid, is provided. The neonicotinoid may be imidacloprid. In use, the dosage regime may be sublethal and/or lethal.