Heat-Treated Fish Egg Extract for Skin Rejuvenation

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Solution Overview

Problem

Current methods fail to effectively stimulate fibroblast migration, elastin production, and reduce inflammatory factors in the skin, leading to skin aging and damage, while also lacking in treatments for wound healing and maintaining youthful skin appearance.

Innovation Solution

The use of heat-treated fish egg cellular extracts, formulated into creams, gels, or lotions, which stimulate fibroblast migration, increase hyaluronic acid production, and upregulate specific genes to improve skin health, reduce fine lines, and enhance wound healing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional skin treatments are used, then basic skin maintenance is achieved, but fibroblast migration and elastin production are not effectively stimulated

Engineering Contradiction:
Improvefibroblast migration stimulationVSAvoidskin rejuvenation effectiveness
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies parameter changes by heat-treating the fish egg cellular extract at temperatures of 60-90°C for 1-30 minutes, which modifies the physical and chemical properties of the extract to enhance its bioactivity. This heat treatment process transforms the raw extract into a more effective formulation that can stimulate fibroblast migration and elastin production, directly resolving the contradiction between basic maintenance and effective rejuvenation.

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If no specific treatment is applied, then skin aging and damage progress, but existing treatments lack effectiveness in reducing inflammatory factors

Engineering Contradiction:
Improveinflammatory factors expressionVSAvoidskin health improvement
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent extracts and isolates specific bioactive components from fish egg cellular material through heat treatment and formulation processes. This extraction of concentrated active ingredients from the raw egg material creates a targeted treatment that specifically addresses inflammatory factors in the skin, moving beyond general skin maintenance to focused anti-inflammatory action.

Inventive Principle:
Principle #2Taking out (Extraction)

3Productivity

If basic skin care is provided, then skin function is maintained, but wound healing and youthful appearance are not restored

Engineering Contradiction:
Improvewound healing rateVSAvoidskin appearance restoration
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies preliminary action by pre-treating the fish egg cellular extract with heat before application to the skin. This pre-processing step activates and stabilizes the bioactive components in advance, ensuring they are in optimal form to stimulate wound healing and restore youthful skin appearance upon contact with the skin, rather than relying on raw, unprocessed material.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The heat-treated fish egg cellular extracts effectively stimulate fibroblast migration, increase elastin production, reduce inflammatory factors, and improve skin hydration, leading to enhanced skin health, reduced fine lines, and improved wound healing, resulting in a more youthful and healthy skin appearance.

Implementation Method 1

heating said extract to a temperature of above about 80 C to provide a heat treated fish egg cellular extract

Methodology Applied
Scientific EffectHeat treatment: Heating

Data Source

PatentUS11007385B2Use of cellular extracts for skin rejuvenation
Publication Date: 2021.05.18 REGENICS AS
  • US11007385B2 patent drawing
  • US11007385B2 patent drawing
  • US11007385B2 patent drawing

AI summary

The invention describes methods and agents for inducing in the skin one or more effects selected from stimulating fibroblast migration, stimulating elastin production, reducing expression of inflammatory factors and upregulating specific genes, thereby preventing skin cell aging processes and repairing skin damage. In preferred embodiments, the methods and agents comprise active extracts produced from fish eggs.