FLASH Radiation Therapy Apparatus with Real-Time Dose Feedback Control

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Solution Overview

Problem

Current radiation therapy technologies face challenges in achieving precise dose control and minimizing tissue disturbance due to the high variability in ultrahigh dose rate radiation used in FLASH irradiation methods, requiring advanced systems for real-time monitoring and adjustment.

Innovation Solution

A radiation therapy apparatus equipped with a processing circuitry that monitors and adjusts the radiation emission period based on real-time dose rate and accumulated dose measurements, using a dosimeter to ensure accurate delivery of the target dose while employing the FLASH irradiation method.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If FLASH irradiation method is used to emit ultrahigh dose rate radiation, then treatment effectiveness on target tissue is improved, but dose control precision deteriorates due to high variability in dose rate

Engineering Contradiction:
Improvedose rateVSAvoiddose control precision
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent implements real-time feedback control by measuring the actual dose rate and accumulated dose during FLASH irradiation, then using this information to adjust the radiation emission timing. The control unit continuously monitors dosimeter readings and modifies the irradiation schedule to maintain precise dose delivery despite high dose rate variability, directly resolving the contradiction between achieving ultrahigh dose rates and maintaining dose control precision.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system dynamically adjusts the radiation emission timing based on real-time dose rate measurements and accumulated dose calculations. The control unit modifies the irradiation schedule on-the-fly, adapting to fluctuations in dose rate to ensure accurate dose delivery. This dynamic adjustment capability allows the system to maintain precision while operating at ultrahigh dose rates.

Inventive Principle:
Principle #15Dynamics

2Manufacturing precision

If real-time monitoring and adjustment of radiation emission is implemented, then dose delivery precision is improved, but device complexity increases

Engineering Contradiction:
Improvedose delivery precisionVSAvoidmonitoring and control system complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The control unit performs multiple functions including measuring dose rate, calculating accumulated dose, determining emission timing, and adjusting radiation emission. By consolidating these functions into a single integrated control system, the patent reduces overall device complexity while maintaining high dose delivery precision. The dosimeter also serves dual purposes for monitoring and control feedback.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution enhances the precision of radiation dose delivery, maintaining effective treatment outcomes while minimizing tissue disturbance by enabling precise control over the high dose rate radiation emission.

Implementation Method 1

processing circuitry configured to measure a dose of the radiation emitted from the radiation generator

Methodology Applied
Scientific EffectRadiation dose measurement: Radiation

Data Source

PatentUS12161887B2Radiation therapy apparatus and radiation therapy method
Publication Date: 2024.12.10 CANON MEDICAL SYST CORP
  • US12161887B2 patent drawing
  • US12161887B2 patent drawing
  • US12161887B2 patent drawing

AI summary

A radiation therapy apparatus according to an embodiment includes a radiation generator and processing circuitry. The radiation generator is configured to emit radiation having an ultrahigh dose rate. The processing circuitry is configured to measure a dose of the radiation emitted from the radiation generator over a period of time. The processing circuitry is configured to calculate an accumulated dose and a dose rate of the radiation emitted from the radiation generator, on a basis of the dose of the radiation measured over the period of time. The processing circuitry is configured to control the radiation generator, on a basis of the dose of the accumulated dose and the dose rate.