Flavone Oral Products for Cognitive Boost With Reduced Jitteriness

Resolve Bottlenecks,
Find Innovative SolutionsGenerate Solutions

Solution Overview

Problem

Existing oral products that provide cognitive enhancement and energy boosts, such as those containing caffeine, often cause undesirable effects like jitteriness, increased heart rate, and fatigue, which limits their effectiveness and user satisfaction.

Innovation Solution

The use of flavones, specifically compounds of Formula (I), as adenosine receptor antagonists, which provide similar cognitive and energy benefits to caffeine while reducing undesirable effects like jitteriness through alternative mechanisms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If caffeine is used to provide stimulant effects and cognitive enhancement, then alertness and cognitive performance are improved, but jitteriness and adverse physiological effects increase

Engineering Contradiction:

Improvecognitive enhancement effectVSAvoidjitteriness

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameter by substituting caffeine with flavone compounds (quercetin, kaempferol, isorhamnetin, myricetin) that have different molecular structures and receptor binding characteristics. These flavones provide adenosine receptor antagonism and other stimulant effects without the harmful jitteriness associated with caffeine, while maintaining cognitive enhancement benefits.

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent employs flavone compounds that can be administered in oral products with rapid onset and duration characteristics. These compounds provide the necessary stimulant effects temporarily without causing prolonged adverse effects like jitteriness, allowing for effective cognitive enhancement with minimal harm.

Inventive Principle:

Principle #27Cheap short-living objects (Disposable)

2Reliability

If caffeine is used to increase energy levels, then alertness is improved, but heart rate and other physiological parameters increase adversely

Engineering Contradiction:

Improveenergy level enhancementVSAvoidincreased heart rate

Core Design Contradiction:

ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent changes the pharmacological parameter by using flavone compounds that act on different receptor systems. These flavones provide energy enhancement through adenosine receptor antagonism and other mechanisms without the direct cardiovascular stimulation that causes increased heart rate with caffeine, thus improving energy levels with a safer physiological profile.

Inventive Principle:

Principle #35Parameter changes

3Reliability

If caffeine is used to provide stimulant effects, then cognitive performance is improved, but fatigue and crash occur after initial effects

Engineering Contradiction:

Improvecognitive performanceVSAvoidsustained energy levels

Core Design Contradiction:

ReliabilityVSDuration of action of moving object

Solution Approach 1:

The patent changes the temporal parameter of the stimulant effect by using flavone compounds with different pharmacokinetic profiles. These compounds provide sustained adenosine receptor antagonism and cognitive enhancement without the rapid onset and offset characteristic of caffeine, eliminating the crash phenomenon while maintaining prolonged alertness and energy levels.

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Flavones like those of Formula (I) enhance cognitive performance, alertness, and energy levels with reduced jitteriness and other adverse effects, offering a more favorable physiological profile compared to caffeine.

Implementation Method 1

Flavones such as quercetin, kaempferol, isorhamnetin, and myricetin, or combinations thereof, are used to increase cognitive performance, alertness and/or energy levels of a human or animal. The flavones act as adenosine receptor antagonists.

Methodology Applied

Scientific EffectAdenosine receptor antagonism:

Data Source

PatentEP4631502A1Use of flavones such as quercetin to increase cognitive function and to reduce jitterness

Publication Date: 2025.10.15 NICOVENTURES TRADING LTD

AI summary

The present disclosure relates to uses of compounds or combinations thereof to increase cognitive performance, alertness and/or energy levels of a human or animal, as well as an oral product comprising said compounds or combinations thereof.