Flexible Brain Electrode with Deep Implantation

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Solution Overview

Problem

Current brain electrodes, such as cerebral cortex electrodes, face challenges in signal recording and stimulation due to material defects and structural limitations, and lack the capability to simultaneously monitor surface and deep neural signals effectively.

Innovation Solution

A flexible electrode for the brain is designed with a cortical attachment portion and deep implantation portions, featuring a multilayer structure with insulating layers and a wire layer, allowing for simultaneous recording and stimulation of both surface and deep neural signals.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If conventional rigid electrodes are used for brain recording and stimulation, then structural stability is maintained, but tissue trauma increases and long-term stability deteriorates

Engineering Contradiction:
Improvetissue traumaVSAvoidelectrode structural stability
Core Design Contradiction:
Object-affected harmful factorsVSStability of the object's composition

Solution Approach 1:

The patent employs flexible thin film structures for the electrode substrate, allowing the electrode to conform to the brain surface and reduce mechanical mismatch. This flexibility minimizes tissue trauma while maintaining structural integrity through the engineered thin film composition and design.

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The electrode utilizes composite material structures combining flexible substrates with conductive elements and insulating layers. This composite approach enables the electrode to achieve both flexibility for reduced tissue damage and structural stability for long-term operation.

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If single-layer electrode structures are used, then manufacturing simplicity is maintained, but the capability to simultaneously monitor surface and deep neural signals is insufficient

Engineering Contradiction:
Improvesimultaneous surface and deep signal monitoring capabilityVSAvoidelectrode structure complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The electrode is divided into multiple functional layers with distinct purposes: flexible substrate, conductive traces, insulating layers, and electrode contact points. This segmentation enables simultaneous surface and deep signal monitoring while maintaining manufacturability through standardized layer-by-layer fabrication processes.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The electrode design transitions from planar to three-dimensional configurations with elevated contact points that can reach deep neural structures while the base remains on the brain surface. This dimensional approach enables multi-depth monitoring without significantly increasing manufacturing complexity.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Measurement precision

If traditional electrode materials are used, then material availability is maintained, but signal recording precision and stimulation effectiveness are limited

Engineering Contradiction:
Improvesignal recording precisionVSAvoidmaterial availability and processing ease
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The electrode employs composite material structures combining flexible substrates with conductive elements and insulating layers. This composite approach enables the electrode to achieve both flexibility for reduced tissue damage and structural stability for long-term operation.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS20250114595A1Flexible electrode for brain and method for manufacturing same
Publication Date: 2025.04.10 CENT FOR EXCELLENCE IN BRAIN SCI & INTELLIGENCE TECH CHINESE ACAD OF SCI
  • US20250114595A1 patent drawing
  • US20250114595A1 patent drawing
  • US20250114595A1 patent drawing

AI summary

The present disclosure relates to a flexible electrode for a brain and a method for manufacturing the same. Provided is a flexible electrode for the brain, which comprises a cortical attachment portion that can be implanted into the brain, and one or more deep implantation portions, the cortical attachment portion having a sheet-like structure capable of covering and being flattened to fit against at least a portion of a cerebral cortex after implantation, and the deep implantation portions being configured to be implanted into a deep region of the brain and bent relative to the cortical attachment portion after implantation, wherein the deep implantation portions and the cortical attachment portion each comprise one or more electrode sites, each of the electrode sites being electrically coupled to one of wires in the wire layer and being in contact with the brain after the flexible electrode is implanted into the brain.