Flexible-Filter Adipose Tissue Purification for Reproducible Processing

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Solution Overview

Problem

Current autologous adipose tissue transplantation procedures lack reproducibility and are costly due to manual preparation by operators, leading to potential errors and high resorption rates of reintroduced fat.

Innovation Solution

A device with a flexible filter and drive system that centrifuges and discharges adipose tissue, removing contaminants through a purification configuration and winding the filter for discharge, ensuring high-quality, low-resorption adipose tissue reintroduction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual preparation of adipose tissue is performed by operators, then flexibility and adaptability are maintained, but manufacturing precision and reliability deteriorate due to potential errors and lack of reproducibility

Engineering Contradiction:
Improvereproducibility of adipose tissue preparationVSAvoidcomplexity of preparation system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces manual mechanical preparation operations with an automated centrifugal purification system. The device uses a centrifugal mechanism to automatically separate adipose tissue from contaminants and washing liquid, eliminating operator involvement and ensuring reproducible results. The centrifugal force field automatically performs the separation function that previously required manual handling and filtering operations.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If manual preparation methods are used, then operational flexibility is maintained, but productivity deteriorates due to time-consuming procedures and high operational costs

Engineering Contradiction:
Improveefficiency of adipose tissue preparationVSAvoidsimplicity of preparation process
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The centrifugal purification device performs the separation function automatically without requiring operator intervention during the purification process. The system self-regulates the centrifugal separation, automatically discharges contaminants through the filter, and prepares the adipose tissue for collection. This self-service capability significantly improves productivity by eliminating manual preparation steps while maintaining operational simplicity through automated control.

Inventive Principle:
Principle #25Self-service

3Manufacturing precision

If centrifugal purification is implemented, then manufacturing precision and purity are improved, but device complexity increases due to additional mechanical components

Engineering Contradiction:
Improvepurity of purified adipose tissueVSAvoidcomplexity of centrifugal mechanism
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The centrifugal mechanism serves multiple functions simultaneously: it provides the centrifugal force field for separation, drives the rotation of the filter for contaminant discharge, and controls the overall purification process timing. This multi-functionality reduces the need for separate mechanical components for each function, thereby limiting the increase in device complexity while achieving high purification precision through centrifugal separation.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device simplifies and enhances the reliability of adipose tissue purification, reducing resorption rates and operational costs by automating the process while maintaining high tissue quality.

Implementation Method 1

the ends of the filter are connected to separate attachment elements whose movement is controlled differently by the drive system depending on whether it is desired to purify the adipose tissue or to carry out the discharge. Thus, in the purification configuration, the lower and upper ends of the filter rotate together, which leads to centrifugation of the adipose tissue against the internal wall of the filter

Methodology Applied
Scientific EffectCentrifugal force: Centrifugal Force

Implementation Method 2

a flexible filter delimiting a treatment volume and being able to retain the adipose tissue and to filter a liquid medium

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 3

when the drive system is put into the discharge configuration, one end of the filter is rotated with relative movement with regard to the other end, which can be fixed by being no longer engaged with the drive system. This causes the filter to wind on itself from its upper end (area of least stress with no adipose tissue, or less adipose tissue than in the lower end) to its lower end. This winding applies discharge pressure that pushes purified adipose tissue into the discharge duct

Methodology Applied
Scientific EffectMechanical compression: Compression

Data Source

PatentUS20250303051A1Device for purifying adipose tissue
Publication Date: 2025.10.02 MICROAIRE SURGICAL INSTR LLC
  • US20250303051A1 patent drawing
  • US20250303051A1 patent drawing
  • US20250303051A1 patent drawing

AI summary

A device for purifying adipose tissue may comprise a chamber, a flexible filter delimiting a treatment volume and being able to retain the adipose tissue and to filter a liquid medium, the filter being present in the chamber and extending along a main axis between a lower end and an upper end, a lower attachment element secured to the lower end of the filter and an upper attachment element secured to the upper end of the filter, a discharge duct extending into the treatment volume between a lower portion provided with the inlet orifice and an upper portion in communication with the outside of the device, and a drive system configured to take a purification configuration in which the lower and upper attachment elements are rotated jointly around the main axis and configured to take a discharge configuration.