Flexible Hemostatic Sponge Using Modified Potato Starch
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Solution Overview
Problem
Conventional hemostatic agents in powder form are inconvenient for application, especially in sensitive areas like the nose, gums, or back, and lack flexibility, making it difficult to handle and apply effectively.
Innovation Solution
A flexible hemostatic sponge made from polysaccharides such as modified pregelatinized potato starch, combined with binding agents and clotting accelerators, which can be applied to wounds to promote rapid and stable clotting, and is designed to maintain flexibility without cracking or tearing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If hemostatic agents are used in powder form, then they can be easily stored and transported, but they are difficult to handle and apply to various body areas
Solution Approach 1:
The patent transforms the physical state of the hemostatic agent from powder to a flexible sponge form. This parameter change (from particulate to porous solid structure) maintains the hemostatic functionality while dramatically improving ease of application to various body areas including nose, gums, and back, eliminating the handling difficulties associated with powder form.
Solution Approach 2:
The invention uses composite materials combining starch (hemostatic agent) with binders and porogens to create a flexible sponge structure. This composite approach integrates the hemostatic properties of starch with the structural advantages of a sponge matrix, achieving both effective clotting and easy applicability to challenging wound locations.
2Reliability
If conventional hemostatic agents are used, then they can promote clotting, but they lack flexibility and are difficult to manipulate without cracking or tearing
Solution Approach 1:
The patent creates a flexible sponge structure that can be manipulated without cracking or tearing. The porous foam matrix provides flexibility and conformability while maintaining the hemostatic agent's clotting promotion capability, allowing the material to adapt to various wound shapes and locations.
Solution Approach 2:
The invention changes the physical form parameter from rigid or brittle powder to a flexible porous solid. This parameter transformation enables the hemostatic agent to be easily manipulated, bent, and applied to irregular body surfaces while preserving its biological function of promoting rapid clotting.
3Ease of operation
If a flexible hemostatic sponge is created, then it can be easily applied to various body areas, but it may compromise the stability and effectiveness of the hemostatic agent
Solution Approach 1:
The patent employs composite materials where starch (the hemostatic agent) is integrated within a binder matrix containing porogens. This composite structure ensures that the flexible sponge form does not compromise hemostatic effectiveness, as the starch particles remain distributed and functional within the porous structure, maintaining their ability to promote stable clotting.
Solution Approach 2:
The invention uses a porous foam structure that maintains high surface area and absorptive capacity while providing flexibility. The porous architecture allows blood to penetrate and interact with the hemostatic agent particles, ensuring that application ease does not reduce hemostatic effectiveness.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The sponge allows for easy and effective application to various body areas, promoting rapid clotting and stable wound closure, even in challenging locations, while being easy to use and non-toxic.
Implementation Method 1
The sponge comprises a starch having hemostatic properties
Implementation Method 2
promote rapid clotting and stable wound closure
Data Source
AI summary
A sponge including one or more hemostatic agents and one or more binding agents. At least one of the hemostatic agents is a pregelatinized potato starch. The collective percentage by weight of the one or more hemostatic agents is within the range of approximately one eighth to approximately sixteen times as great as the collective percentage by weight of the one or more binding agents.