Flexible SEEG Electrode Bonding for Multi-Channel Single-Cell Sensing
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Solution Overview
Problem
Existing SEEG technology is limited by volume, channel count, and electrode site size, preventing accurate EEG data acquisition and electrical stimulation at the single-cell level, and lacks extendibility for other functions.
Innovation Solution
A flexible electrode apparatus is attached to the SEEG electrode without adhesives, comprising a multi-layer structure with insulating layers, wire layers, and electrode sites, allowing for multi-channel, single-cell-level precise EEG signal acquisition and electrical stimulation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If adhesive is used to attach flexible electrode to SEEG electrode, then attachment strength is improved, but SEEG electrode size and surgical process are affected
Solution Approach 1:
The flexible electrode structure utilizes its own mechanical properties (flexibility and conformability) to achieve attachment to the SEEG electrode without requiring external adhesives. The electrode's design allows it to wrap around and secure to the SEEG electrode through its inherent physical characteristics, making the attachment process self-sufficient and avoiding additional materials that would complicate the device or surgical procedure.
2Adaptability or versatility
If SEEG electrode is used for basic positioning, then surgical simplicity is maintained, but functional versatility is limited
Solution Approach 1:
The flexible electrode is designed to provide multiple functions including EEG signal acquisition, electrical stimulation, and potential integration with other therapeutic or diagnostic modalities. By incorporating these diverse functionalities into a single flexible electrode structure that can be attached to the SEEG electrode, the system achieves multi-functionality without requiring separate dedicated devices, thus improving versatility while managing overall device complexity.
3Measurement precision
If traditional electrode structures are used, then manufacturing simplicity is maintained, but measurement precision for single-cell level is insufficient
Solution Approach 1:
The flexible electrode employs thin-film construction that enables it to conform closely to the SEEG electrode surface and achieve fine spatial resolution for single-cell level measurements. The flexible nature of the thin film allows it to adapt to curved surfaces and maintain intimate contact, which is critical for high-precision electrical signal acquisition at the cellular level, while the thin-film technology itself provides a manufacturable solution for achieving this precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables firm attachment of the flexible electrode to the SEEG electrode without affecting its size or surgical process, expanding its functions to include multi-channel, single-cell-level precise EEG signal acquisition and electrical stimulation.
Implementation Method 1
causing the SEEG electrode to be in contact with and attached to a root portion of the flexible electrode in pure water
Implementation Method 2
baking the assembly to enhance adhesion between the SEEG electrode and the flexible electrode
Data Source
AI summary
A flexible electrode apparatus for bonding with a SEEG electrode includes: at least one wire electrode which is implantable and flexible, wherein each wire electrode includes: a wire located between a first insulating layer and a second insulating layer of the flexible electrode; and an electrode site located on the second insulating layer and electrically coupled to the wire via a through hole in the second insulating layer, wherein the at least one wire electrode is configured to be affixed to the SEEG electrode and is in contact with a biological tissue after the SEEG electrode is implanted.