Flexible Thermoelectric Heat Exchange Module for Precise Patient Temperature Control

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Solution Overview

Problem

Current hypothermia treatments using ice packs and chilled fluid systems provide incomplete and short-lived cooling, lacking the precision and efficiency needed for therapeutic applications such as brain injuries and chemotherapy side effects.

Innovation Solution

A flexible heat exchange module (HEM) with thermoelectric coolers (TECs) that includes a heat transfer fluid channel, a heat transfer plate, and a thermistor to measure skin temperature, allowing for controlled heating or cooling through a control unit that manages the operation of the TECs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If ice packs and chilled fluid systems are used for hypothermia treatment, then cooling can be provided, but the cooling is incomplete and short-lived

Engineering Contradiction:
Improveduration of coolingVSAvoidcompleteness of cooling
Core Design Contradiction:
Duration of action of moving objectVSReliability

Solution Approach 1:

The patent implements continuous cooling through a closed-loop fluid circulation system where chilled fluid continuously circulates through heat exchange channels in contact with the patient's body. This eliminates the short-lived cooling of ice packs by maintaining sustained heat removal over extended periods through pump-driven fluid circulation and continuous phase change cooling.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent utilizes phase transition of refrigerant in thermoelectric coolers (TECs) to provide continuous cooling. The TECs employ phase change materials that absorb heat from the patient's body during phase transition, enabling prolonged and reliable cooling that overcomes the limitations of conventional ice packs and chemical cool packs.

Inventive Principle:
Principle #36Phase transitions

2Measurement precision

If conventional cooling methods are used, then cooling can be achieved, but precision and efficiency for therapeutic applications are lacking

Engineering Contradiction:
Improvetemperature control precisionVSAvoidcooling efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent implements temperature feedback control through thermistors positioned in thermal contact with the patient's skin, which continuously monitor temperature and feed signals to a controller. The controller adjusts TEC operation based on this feedback, achieving precise temperature control within ±0.5°C while optimizing cooling efficiency for therapeutic applications.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces conventional mechanical cooling systems with thermoelectric cooling technology. The TECs use electrical current directly to create cooling effects through the Peltier effect, eliminating the need for compressors, condensers, and other mechanical components, thereby improving precision and efficiency while reducing system complexity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Speed

If thermoelectric coolers are used for temperature control, then rapid and precise cooling can be achieved, but device complexity increases

Engineering Contradiction:
Improvecooling speedVSAvoidsystem complexity
Core Design Contradiction:
SpeedVSDevice complexity

Solution Approach 1:

The patent divides the cooling system into modular segments: multiple independent TEC modules arranged in arrays, each with its own heat exchange channels and temperature sensors. This segmentation allows parallel cooling zones that operate independently, achieving rapid overall cooling while distributing system complexity across manageable modules that can be configured for different body regions.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent designs a universal cooling platform where TEC modules can be configured for various therapeutic applications (hypothermia, hyperthermia, regional cooling) by adjusting parameters such as fluid flow rate, TEC power output, and module arrangement. This multi-functionality reduces overall system complexity by using a single platform for multiple purposes rather than requiring separate systems for each application.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Adaptability or versatility

If flexible heat exchange modules are implemented, then adaptability to body contours is improved, but manufacturing complexity increases

Engineering Contradiction:
Improveadaptability to body contoursVSAvoidmanufacturing complexity
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The patent employs flexible heat exchange modules with thin-film construction that can conform to body contours. The modular design uses flexible channels and compressible elements that allow the module to adapt to various body shapes and positions, improving patient comfort and treatment effectiveness while maintaining manufacturability through standardized flexible component production.

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The HEM system enables rapid and precise temperature control, achieving cooling to below 10°C in minutes and heating to 40°C in two minutes, with stable temperature maintenance for therapeutic applications, enhancing treatment efficacy for conditions like brain injuries and chemotherapy side effects.

Implementation Method 1

A flexible heat exchange module (HEM) with thermoelectric coolers (TECs) that includes a heat transfer fluid channel, a heat transfer plate, and a thermistor to measure skin temperature

Methodology Applied
Scientific EffectThermoelectric cooling: Peltier Effect

Implementation Method 2

A thermistor mounted on the tile measures the temperature of the body part against which the tile is positioned and sends the temperature signal to a controller

Methodology Applied
Scientific EffectThermistor temperature sensing: Thermistor

Implementation Method 3

heat transfer plate in heat transfer relation with fluid in the channel. The reference side of a thermoelectric cooler (TEC) is in thermal contact with the plate

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentEP3518843B1Heat exchange module, system and method
Publication Date: 2024.06.26 HYPOTHERMIA DEVICES INC
  • EP3518843B1 patent drawingFigure 1
  • EP3518843B1 patent drawingFigure 2
  • EP3518843B1 patent drawingFigure 3

AI summary

A heat exchange module having a heat transfer fluid channel and a heat transfer plate in heat transfer relation with fluid in the channel. The reference side of a thermoelectric cooler (TEC) is in thermal contact with the plate. A heat transfer tile is in thermal contact with a user side of the TEC. The module is configured to be operatively positionable with the tile in heat transfer relation with skin of a patient.