Fluorescence Measurement Error Modeling for Flow Cytometry
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Solution Overview
Problem
Flow cytometers face challenges in accurately measuring particle characteristics due to various errors associated with measurement conditions, leading to a need for a technique to estimate and correct these errors.
Innovation Solution
An information processing apparatus and method that utilize a database of measurement results and simulation data to generate a calculation formula that quantitatively represents the error amount in measurement results, based on input measurement conditions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If a large number of applications are displayed in a list format, then users can access various applications, but the display screen becomes cluttered and difficult to operate
Solution Approach 1:
The patent segments the application list into multiple pages, with each page displaying a subset of applications. Users can navigate between pages to access different groups of applications, preventing screen clutter while maintaining access to all applications through structured division of the application set.
2Area of stationary object
If icons are arranged in a grid pattern, then screen space is utilized efficiently, but users have limited control over icon placement and customization
Solution Approach 1:
The patent implements a dynamic icon arrangement system where icons can be freely moved and repositioned by users within the grid structure. The system adapts to user preferences by allowing custom placement while maintaining the overall grid organization, combining efficient space utilization with flexible customization capability.
3Loss of information
If detailed application information is displayed, then users can make informed decisions, but the interface becomes complex and harder to navigate
Solution Approach 1:
The patent implements a progressive information disclosure mechanism where users interact with icons in stages - first seeing basic icon representations, then accessing detailed information through sequential actions like clicking or long-pressing. This periodic revelation of information levels provides complete details when needed while maintaining a simple initial interface view.
Data Source
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AI summary
To provide an information processing apparatus and an information processing method capable of easily calculating an error amount included in a measurement value. An information processing apparatus includes: an extraction unit configured to extract each parameter variation that affects fluorescence intensity that is measured when a particle is irradiated with a light beam, from a database on the basis of a measurement condition; and a computation unit configured to generate a calculation formula representing an error amount included in the fluorescence intensity on the basis of the extracted each parameter variation.