FLOWCUT Lettuce Cultivar Genome Editing for Yield and Disease Resistance

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Solution Overview

Problem

Current lettuce cultivars lack stable, high-yielding varieties with improved agronomic and horticultural qualities, such as enhanced disease resistance, drought tolerance, and increased nutritional content, which are essential for maximizing yield and adaptability in varying environmental conditions.

Innovation Solution

Development of the novel lettuce cultivar FLOWCUT, which includes specific physiological and morphological characteristics, such as disease resistance, improved yield, and nutritional enhancements, achieved through breeding techniques like backcrossing and genome editing using New Breeding Techniques (NBTs) to introduce desired traits like herbicide resistance, drought tolerance, and increased sugar content.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional breeding methods are used to develop lettuce cultivars, then basic yield is maintained, but disease resistance and drought tolerance are insufficient

Engineering Contradiction:
Improvedisease resistanceVSAvoiddrought tolerance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent applies genome editing technology to precisely modify genetic parameters of lettuce cultivars, introducing specific traits such as disease resistance genes and drought tolerance genes. This enables targeted changes in genetic parameters to simultaneously improve multiple agronomic qualities that were previously difficult to achieve through conventional breeding.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates composite genetic structures by combining multiple desirable traits (disease resistance, drought tolerance, nutritional content) into a single integrated cultivar. Through backcrossing and genome editing, multiple genetic elements are combined to produce a composite cultivar with enhanced overall performance.

Inventive Principle:
Principle #40Composite materials

2Productivity

If conventional breeding techniques are used, then cultivar development is achieved, but nutritional content and yield enhancement are limited

Engineering Contradiction:
ImproveyieldVSAvoidnutritional content
Core Design Contradiction:
ProductivityVSQuantity of substance

Solution Approach 1:

The patent uses genome editing to precisely modify genetic parameters controlling yield and nutritional content. Specific genes associated with sugar content, vitamin content, and yield parameters are targeted for enhancement, allowing simultaneous improvement of both productivity and nutritional quality that exceeds conventional breeding capabilities.

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If existing lettuce cultivars are used, then basic agronomic performance is maintained, but adaptability to varying environmental conditions is insufficient

Engineering Contradiction:
Improveenvironmental adaptabilityVSAvoidplant vigor
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent modifies genetic parameters to enhance environmental adaptability while maintaining plant vigor. Specific genetic modifications enable the cultivar to adapt to varying environmental conditions (drought, disease pressure) while preserving robust growth characteristics through careful selection and backcrossing.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS11785905B2Lettuce named FLOWCUT
Publication Date: 2023.10.17 VILMORIN MIKADO
  • US11785905B2 patent drawing

AI summary

Novel lettuce, such as lettuce designated FLOWCUT is disclosed. In some embodiments, the disclosure relates to the seeds of lettuce designated FLOWCUT, to the plants and plant parts of lettuce designated FLOWCUT, and to methods for producing a lettuce plant by crossing the lettuce designated FLOWCUT with itself or another lettuce plant. The disclosure further relates to methods for producing a lettuce plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other lettuce plants derived from the lettuce designated FLOWCUT.