Post-Harvest Fludioxonil-Azoxystrobin Composition for Storage Disease Control
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Solution Overview
Problem
Current fungicide compositions for post-harvest protection of sugar beets, potatoes, and corm vegetables face issues with resistance development in fungal populations and inadequate residue levels, leading to partial or total loss of control over storage diseases.
Innovation Solution
A composition comprising fludioxonil and azoxystrobin, without difenoconazole, is applied post-harvest to enhance residue levels and manage resistance, using methods such as spray application and compatibility testing to ensure effective coverage.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If the same group of fungicides is used repeatedly or in successive years as the primary method of control, then storage diseases can be controlled initially, but fungal resistance develops leading to partial or total loss of control
Solution Approach 1:
The patent combines two different fungicide modes of action (fludioxonil - phenyl pyrrole group, and azoxystrobin - strobilurin group) into a single composition. This merging of different chemical classes with distinct mechanisms of action prevents fungal resistance by ensuring that fungi cannot develop resistance to both modes simultaneously, thereby maintaining reliable control effectiveness over time
Solution Approach 2:
The patent employs different chemical classes (Group 12 phenyl pyrrole and Group 11 strobilurin) with different modes of action to control fungi. By changing the chemical parameters and mechanisms rather than repeating the same fungicide group, the composition prevents resistance development while maintaining effective disease control
2Quantity of substance
If application rates of fungicides are too low, then cost and residue concerns are reduced, but resistant populations develop leading to loss of control
Solution Approach 1:
The composition merges fludioxonil and azoxystrobin to achieve synergistic or additive effects that enhance control effectiveness at lower individual application rates. The combined action of two fungicides with different modes of action provides robust disease control even when applied at reduced rates, preventing resistance while maintaining effectiveness
Solution Approach 2:
The patent creates a composite fungicide composition containing fludioxonil and azoxystrobin. This composite material leverages the complementary properties of both fungicides to achieve superior control at lower overall application rates, reducing the selective pressure for resistance while maintaining reliable disease management
3Reliability
If fludioxonil and azoxystrobin are used together, then higher residues are achieved and disease control is enhanced, but the composition complexity increases
Solution Approach 1:
The patent merges fludioxonil and azoxystrobin into a single integrated composition that achieves enhanced disease control and higher residues. While the composition contains two active ingredients, they are formulated as a unified product with a single mode of application, avoiding the complexity of managing multiple separate fungicide applications
Solution Approach 2:
The composition serves multiple functions simultaneously: fludioxonil provides control against certain fungal pathogens while azoxystrobin addresses others, and together they achieve enhanced overall disease control. This multi-functionality is achieved through a single application process, maintaining operational simplicity despite the enhanced performance
Data Source
AI summary
Methods of post-harvest protection by spraying a harvested crop of sugar beets, potatoes, or corm vegetables with a composition comprising fludioxonil and azoxystrobin, wherein the only active ingredients in the composition fludioxonil and azoxystrobin.


