Fludioxonil Colorimetric Detection Using p-DAB or DMACA

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Solution Overview

Problem

Existing methods lack a reliable and efficient process for determining the fludioxonil content in liquid media using colorimetric analysis.

Innovation Solution

A colorimetric process involving a reaction with [4-(dimethylamino)phenyl]methanol (p-DAB) or 4-Dimethylaminocinnamaldehyde (DMACA) and an acid is employed to create a colorimetric reading, using reference samples for comparison, to determine fludioxonil content in liquid media.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If colorimetric analysis is performed to determine fludioxonil content, then measurement capability is provided, but existing methods lack reliability and efficiency

Engineering Contradiction:
Improvefludioxonil content determination accuracyVSAvoidmeasurement reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent employs colorimetric analysis where fludioxonil reacts with p-DAB indicator in the presence of acid to produce a color change. The intensity of the color developed is proportional to the fludioxonil concentration, enabling quantitative measurement through colorimetric reading or visual comparison with reference samples of known concentrations.

Inventive Principle:
Principle #32Color changes

Solution Approach 2:

The patent introduces p-DAB (4-(dimethylamino)phenyl]methanol) as an intermediary indicator substance that mediates the detection of fludioxonil. The indicator reacts specifically with fludioxonil in the presence of acid to produce a measurable color signal, serving as a reliable intermediary for quantification.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If colorimetric analysis is performed to determine fludioxonil content, then measurement capability is provided, but existing methods lack efficiency

Engineering Contradiction:
Improvefludioxonil content determination accuracyVSAvoidmeasurement efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent replaces complex mechanical or instrumental analytical systems with a simplified colorimetric system. Instead of using sophisticated equipment for fludioxonil detection, the method uses chemical reaction-based color development that can be measured with simple colorimeters or even visual comparison, significantly improving measurement efficiency and accessibility.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If reference samples are used for comparison, then measurement accuracy is improved, but process complexity increases

Engineering Contradiction:
Improvefludioxonil content determination accuracyVSAvoidprocess complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent creates reference samples that are copies or replicas of actual samples with known fludioxonil concentrations. These reference samples replicate the matrix and conditions of test samples, providing a basis for direct visual or instrumental comparison. This copying approach simplifies the measurement process by eliminating the need for complex calibration curves or standard addition methods.

Inventive Principle:
Principle #26Copying

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate and efficient determination of fludioxonil concentration through visual or colorimetric comparison, facilitating precise quantification.

Implementation Method 1

performing a color reaction with [4-(dimethylamino)phenyl]methanol (p-DAB) or 4-Dimethylaminocinnamaldehyde (DMACA) and an acid in the presence of fludioxonil

Methodology Applied
Scientific EffectColor reaction:

Data Source

PatentUS12560545B2Colorimetric measurement of fludioxonil
Publication Date: 2026.02.24 SYNGENTA CROP PROTECITON AG
  • US12560545B2 patent drawing

AI summary

A process for determining the fludioxonil content in a liquid medium by performing a color reaction with [4-(dimethylamino)phenyl]methanol (p-DAB) or 4-Dimethylaminocinnamaldehyde (DMACA) and an acid in the presence of fludioxonil and obtaining a colorimetric reading for the resulting mixture after a period of time.