Biological Fluid Cap Venting for Sterile Localized Extraction
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current cellular-separation systems fail to maintain sterile conditions during the entire process of delivery, incubation, and extraction of biological fluids, and do not allow for localized extraction of fluid components.
Innovation Solution
A cap system with vented ports and a penetrable flexible seal for biological-fluid containers, enabling sterile conditions and localized extraction through a needle or syringe, with vented caps releasing pressure to facilitate fluid insertion and extraction.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a cap system with vented ports and penetrable flexible seal is used, then sterile conditions are maintained throughout the process, but device complexity increases
Solution Approach 1:
The cap system is divided into multiple functional components: a main cap body, separate vented caps for injection and extraction ports, and a penetrable flexible seal. Each component performs a specific function, allowing the system to maintain sterility through modular design where each segment can be independently controlled and sealed.
Solution Approach 2:
The penetrable flexible seal acts as an intermediary element between the external environment and the internal sterile chamber. It allows controlled access through needle or syringe insertion while maintaining the sterile barrier, mediating between the need for fluid extraction and the requirement for sterility maintenance.
2Adaptability or versatility
If a cap system with vented ports is used, then localized extraction of biological fluid is enabled, but device complexity increases
Solution Approach 1:
The system provides different access methods at different locations: the penetrable flexible seal allows needle insertion at a specific point for localized extraction, while the vented caps provide access at the top of the container. This local differentiation enables targeted fluid removal from specific zones within the biological fluid container.
Solution Approach 2:
The penetrable flexible seal transitions from a closed sterile barrier to an open access point dynamically when a needle or syringe penetrates it. This dynamic state change allows the system to switch between maintaining sterility and enabling localized extraction at the moment of need.
3Ease of operation
If vented caps are attached to injection and extraction ports, then pressure is released to facilitate fluid insertion and extraction, but device complexity increases
Solution Approach 1:
The vented caps automatically respond to pressure changes within the biological fluid container. When fluid is injected or extracted, the pressure differential causes the vented caps to open or close automatically, regulating pressure without requiring external control mechanisms. This self-regulating behavior simplifies operation despite the added components.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Maintains sterility throughout the process and allows for precise, localized extraction of biological fluid components, enhancing the efficiency and versatility of fluid handling.
Implementation Method 1
the vented cap is attached to the injection port and releases pressure from the biological-fluid container
Implementation Method 2
centrifuging the biological-fluid container to form two or more fractions of the biological fluid
Data Source
AI summary
Methods and systems disclosed herein provide systems and methods for maintaining sterile conditions inside of a biological-fluid container during an entire process of delivery, incubation, centrifugation, and extraction of fluid. The methods and systems also provide systems and methods for localized extraction of a portion of a biological fluid.