Predictive Fluid Capacity Management for Hematocrit Control

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current methods for managing patient blood fluid volume and hematocrit during cardiopulmonary bypass (CPB) are reactionary, failing to account for real-time changes, leading to excessive hemodilution and inadequate oxygen delivery, which can result in perioperative and postoperative morbidities.

Innovation Solution

A system and method that calculates and displays the fluid capacity of a patient to avoid reaching a predetermined low hematocrit limit, taking into account the addition or loss of red blood cell-free or RBC-containing fluids, providing predictive information to healthcare providers to make informed decisions about fluid management during and after surgery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If real-time hematocrit monitoring is implemented during CPB, then hematocrit levels can be tracked, but the system remains reactionary rather than predictive

Engineering Contradiction:
Improvehematocrit level monitoringVSAvoidresponse time to hemodilution
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system calculates fluid capacity and predicts future hematocrit levels before hemodilution occurs, enabling proactive rather than reactive management. By computing how much fluid can be safely added before reaching critical hematocrit thresholds, the system allows healthcare providers to take preliminary actions to prevent excessive hemodilution.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system continuously updates fluid capacity calculations based on real-time inputs of fluid additions and losses, creating a dynamic feedback loop. This allows the predictive model to adapt to changing patient conditions during CPB, maintaining accuracy while enabling proactive decision-making.

Inventive Principle:
Principle #23Feedback

2Adaptability or versatility

If fluid capacity calculations are performed continuously, then predictive fluid management is enabled, but computational complexity increases

Engineering Contradiction:
Improvepredictive fluid management capabilityVSAvoidcalculation system complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system focuses on calculating changes in fluid capacity based on incremental fluid additions and losses rather than performing complete hematocrit calculations from scratch. By tracking delta changes in fluid volume and updating predictions incrementally, the system reduces computational complexity while maintaining adaptability to changing conditions.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If comprehensive fluid tracking is implemented to account for all fluid additions and losses, then accurate hematocrit prediction is achieved, but data collection burden increases

Engineering Contradiction:
Improvehematocrit prediction accuracyVSAvoidfluid tracking operation
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system is designed to work with routine fluid management documentation that is already part of standard CPB care. By integrating with existing fluid tracking workflows and using data that perfusionists and anesthesiologists are already collecting, the system minimizes additional operational burden while maintaining prediction accuracy.

Inventive Principle:
Principle #25Self-service

Data Source

PatentEP3055800B1Surgical and post-surgical fluid management to prevent low hematocrit
Publication Date: 2019.10.30 MEDTRONIC INC
  • EP3055800B1 patent drawingFigure 1
  • EP3055800B1 patent drawingFigure 2
  • EP3055800B1 patent drawingFigure 3

AI summary

Methods, devices and systems provide information regarding fluid capacity of a patient; i.e., the amount of hematocrit free fluid that can be added to the system to avoid reaching, or to just reach but not fall below, a predetermined low hematocrit limit before, during or after surgeries in which hemodilution may be a concern, such as cardiopulmonary bypass, rather than providing only information regarding hematocrit levels. The fluid capacity of the patient may be displayed to allow a health care provider to make decisions regarding effects of addition of fluid to the blood compartment of the patient.