Repeated Fluid Composition Filtration With Dwell Module Control

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing methods for modifying the composition of fluids repeatedly face challenges such as volume changes and increased effort in contaminant separation, making the process management difficult and inefficient.

Innovation Solution

A device comprising multiple modules, including filter units and a dwell module, allows for gentle repeated modification of fluid composition while simultaneously removing contaminants, enabling continuous operation and adjustable volume changes, using filter units and optional static mixers or chromatography modules to manage fluid properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If conventional methods are used to modify fluid composition repeatedly, then composition modification is achieved, but volume changes occur and contaminant separation effort increases

Engineering Contradiction:
Improvefluid compositionVSAvoidfluid volume
Core Design Contradiction:
Stability of the object's compositionVSQuantity of substance

Solution Approach 1:

The device segments the fluid processing into multiple independent modules (first module, second module, dwell module) connected in series. Each module performs a specific function (composition modification or dwelling), allowing the fluid to undergo repeated composition modifications while maintaining volume control through the segmented architecture.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The dwell module acts as an intermediary between the first and second modules for composition modification. It provides a controlled environment where the fluid can dwell for a specified time, enabling composition changes without requiring volume adjustment, thus mediating between composition modification needs and volume stability requirements.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Stability of the object's composition

If conventional methods are used to modify fluid composition repeatedly, then composition modification is achieved, but process management becomes more difficult

Engineering Contradiction:
Improvefluid compositionVSAvoidprocess management
Core Design Contradiction:
Stability of the object's compositionVSEase of operation

Solution Approach 1:

The device incorporates adjustable parameters including dwell time in the dwell module and flow rates through various channels. These dynamic controls allow operators to optimize the composition modification process for different applications, making the system adaptable and easier to manage while achieving repeated composition modifications.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system enables independent control of multiple parameters (dwell time, flow rates, module configuration) to achieve desired composition modifications. By changing these parameters rather than requiring complex procedural adjustments, the system simplifies process management while maintaining composition stability.

Inventive Principle:
Principle #35Parameter changes

3Quantity of substance

If conventional methods are used for contaminant separation, then contaminants are removed, but the effort and complexity increase

Engineering Contradiction:
Improvecontaminant concentrationVSAvoidseparation system complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The device merges composition modification and contaminant separation functions into a single integrated system. The first and second modules can perform composition modification while the dwell module and filter units simultaneously handle contaminant removal, eliminating the need for separate systems and reducing overall complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The modules in the device are designed with multi-functionality. The first and second modules can modify fluid composition while also contributing to contaminant separation, and the dwell module serves both as a residence time controller and a separation enhancement zone, reducing the need for dedicated separate systems.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables efficient and continuous modification of fluid composition with effective contaminant separation, allowing for precise control of pH and volume adjustments, enhancing process efficiency and reducing operational complexity.

Implementation Method 1

The filter unit has at least one first filter medium, at least one retentate channel, at least one second filter medium and at least one permeate channel, arranged so that the first filter medium delimits the supply channel and the retentate channel from one another and the second filter medium delimits the retentate channel and the permeate channel from one another

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Data Source

PatentUS11931733B2Device and method for repeatedly modifying the composition of a fluid
Publication Date: 2024.03.19 SARTORIUS STEDIM BIOTECH GMBH
  • US11931733B2 patent drawing
  • US11931733B2 patent drawing
  • US11931733B2 patent drawing

AI summary

A device and a method for repeatedly modifying the composition of a fluid. The device includes a first module (19) modifying the composition of the fluid, a second module (21) modifying the composition of the fluid and a dwell module (20) with an inlet (8) and an outlet (10). The first module is connected in a fluid-conducting manner to the dwell module inlet and the dwell module outlet is connected in a fluid-conducting manner to the second module. Either the first or the second module is a filter unit, or the first module is a first filter unit and the second module is a second filter unit. The filter unit(s) include(s) at least one first filter medium (4, 14) delimiting a supply channel (2, 12) and a retentate channel (1, 11) and at least one second filter medium (5, 15) delimiting the retentate channel and a permeate channel (3, 13).