Fluid Pressure Pulse Device for Cardiopulmonary Therapy
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current treatments for respiratory disorders such as asthma and COPD lack effective methods for delivering specific sequences of fluid pressure pulses tailored to individual patient needs, which are essential for optimal therapeutic outcomes.
Innovation Solution
A device and method for administering Fluid Pressure Pulses (FPPs) with customizable frequency, pressure amplitude, volume, and duration, synchronized or asynchronous with the patient's physiological cycles, to improve airway treatment efficacy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional respiratory treatments (systemic medications, inhaler therapies) are used, then patient compliance and ease of administration are maintained, but therapeutic efficacy for specific cardiopulmonary conditions is insufficient
Solution Approach 1:
The invention employs pneumatic mechanisms to generate controlled pressure pulses delivered through a mouthpiece into the respiratory tract. A compressor or pump system creates variable pressure waves that are transmitted through the patient's airways to directly affect cardiopulmonary organs, providing a non-pharmaceutical therapeutic approach with adjustable parameters for different conditions
Solution Approach 2:
The device allows dynamic adjustment of multiple parameters including pressure amplitude, pulse frequency, duty cycle, and waveform characteristics. These parameters can be modified in real-time to optimize treatment for specific conditions such as asthma, COPD, or pulmonary edema, enabling personalized therapy protocols without increasing operational complexity
2Reliability
If intrapulmonary percussive devices are used for airway clearance, then some therapeutic effect is achieved, but the impact is not significant enough to become standard care
Solution Approach 1:
The device delivers periodic pressure pulses at controlled frequencies and duty cycles to the respiratory tract. These rhythmic pressure variations create mechanical vibrations and fluid dynamics that enhance mucociliary clearance, promote bronchodilation, and improve gas exchange, providing significant therapeutic impact for airway clearance
Solution Approach 2:
The pressure pulse mechanism generates mechanical vibrations that propagate through the airways and lung tissue. These vibrations dislodge mucus secretions, enhance surfactant distribution, and stimulate respiratory mechanics, achieving substantial therapeutic effects that address the limitations of conventional percussive devices
3Reliability
If phase-controlled chest wall vibrations are applied to improve left ventricle relaxation, then cardiac function is enhanced, but the treatment does not address pulmonary conditions simultaneously
Solution Approach 1:
The device is designed to treat multiple cardiopulmonary conditions through a single unified platform. By delivering pressure pulses through the respiratory tract, it simultaneously affects cardiac function (improving ventricle relaxation and filling), pulmonary function (clearing airways, improving gas exchange), and systemic circulation, making it adaptable to various conditions including heart failure, asthma, and COPD
4Reliability
If chest wall vibrations are used to reduce pulmonary pressure and improve gas exchange, then pulmonary hemodynamics are improved, but the treatment lacks customization for individual patient protocols
Solution Approach 1:
The device features dynamic control capabilities that allow real-time adjustment of pressure pulse parameters including amplitude, frequency, duty cycle, and waveform shape. Pre-programmed protocols can be selected and modified based on individual patient needs and response, enabling customization for different severity levels and treatment stages while maintaining proven therapeutic efficacy
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device enhances patient wellness by improving pulmonary function, reducing pulmonary pressure, increasing oxygenation, and enhancing quality of life through targeted FPP protocols, as measured by various clinical tests and questionnaires.
Implementation Method 1
a fluid oscillator providing a focused fluid column with a series of alternating high and low pressure zones
Implementation Method 2
applying a sequence of pneumatic pulses to the patient's airways through the oral cavity results in therapeutic effects
Implementation Method 3
vibrations over the chest wall at 50 Hz, that were phase controlled, i.e., activated from the onset of isovolumic relaxation to end-diastole, caused a relaxation of the left ventricle
Implementation Method 4
phase controlled, i.e., activated from the onset of isovolumic relaxation to end-diastole
Implementation Method 5
in-phase vibrations (IPV) applied over the chest of COPD patients reduced their mea arterial pulmonary pressure and pulmonary vascular resistance, while increasing their PaO2 and decreasing their PaCO2
Data Source
AI summary
A device for the introduction of a fluid into a human's airway. The air so introduced has a carefully modulated envelope of pressure vs. time. The envelope generally includes sequences of pressurized air packets of controlled frequency and pressures. The device produces the packets using pressurized air occluded by a shutter action that “chops” and interrupts the fluid stream. The vibrations induced by the device within human organs have been shown to have beneficial effects on various bodily systems, such as an increase in heart rate variability, an increase in absorbed oxygen, and a decrease in absorbed CO2.