Fluid Stream Prostate Tissue Resection
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Solution Overview
Problem
Current treatments for benign prostatic hyperplasia (BPH) and prostatic carcinoma often result in significant complications, such as thermal damage, prolonged procedure times, and the need for high-energy equipment, which can lead to incomplete tissue removal and increased patient risk due to the reliance on heat-based methods that cause obstruction and damage to non-glandular tissues.
Innovation Solution
A method and device utilizing a fluid stream to resect prostate tissue, which is forceful enough to remove tissue without heat, allowing for selective resection of glandular tissue while sparing non-glandular tissue, and includes an anchoring mechanism for stability, enabling efficient tissue removal and minimizing complications.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If heat-based methods are used for tissue ablation, then tissue removal is achieved, but thermal damage occurs to non-glandular tissues and complications increase
Solution Approach 1:
The patent replaces thermal energy-based ablation with mechanical energy-based fluid stream resection. The fluid jet delivers mechanical force directly to glandular tissue through hydrodynamic pressure and cavitation effects, eliminating thermal damage to surrounding non-glandular tissues while achieving effective tissue removal.
Solution Approach 2:
The patent changes the energy delivery parameter from thermal (heat) to mechanical (fluid pressure and cavitation). By controlling fluid stream parameters such as pressure, flow rate, and jet velocity, the system achieves selective tissue resection without the harmful thermal side effects of traditional ablation methods.
2Quantity of substance
If high-energy equipment is used for tissue ablation, then tissue removal is effective, but procedure time increases and patient risk increases
Solution Approach 1:
The patent employs hydraulic principles by using a focused fluid jet to deliver high-pressure liquid streams that mechanically resect tissue. The fluid dynamics generate cavitation bubbles and hydrodynamic forces that efficiently remove glandular tissue without requiring prolonged exposure or high-energy equipment, thereby reducing procedure time and patient risk.
3Quantity of substance
If electrosurgical removal is used, then complete tissue removal is achieved, but invasive procedures and complications increase
Solution Approach 1:
The patent substitutes electrosurgical mechanical cutting with fluid-driven mechanical resection. The fluid jet system achieves complete tissue removal through controlled hydraulic forces and cavitation, eliminating the need for invasive electrosurgical instruments and reducing procedural complexity and complications.
4Quantity of substance
If thermal ablation is used, then tissue destruction is achieved, but obstruction and damage to non-glandular tissues occur
Solution Approach 1:
The patent applies local quality by using a focused fluid jet that delivers mechanical energy precisely to glandular tissue only. The hydrodynamic pressure and cavitation effects are concentrated at the jet-tissue interface, enabling selective resection of glandular tissue while leaving non-glandular tissues unaffected, thus avoiding obstruction and damage.
Solution Approach 2:
The patent replaces thermal destruction with mechanical resection using a focused fluid jet. The mechanical energy from the fluid stream selectively removes glandular tissue through hydrodynamic forces without generating thermal damage, preventing obstruction and harm to surrounding non-glandular structures.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The fluid stream resection method significantly reduces procedure time, minimizes thermal damage, and decreases patient risk by allowing immediate symptomatic relief and reducing the need for post-operative catheterization, while providing precise control over tissue removal and visualization.
Implementation Method 1
A fluid stream is directed outwardly from the fluid delivery element toward a wall of the urethral lumen. The fluid stream is sufficiently forceful to remove tissue.
Implementation Method 2
The fluid stream is sufficiently forceful to remove tissue through mechanical resection without heat-based methods
Data Source
AI summary
Prostate treatment using fluid stream to resect prostate tissue, thereby relieving symptoms of conditions such as BPH, prostatitis, and prostatic carcinoma. A device having a fluid delivery element is positioned within a lumen of the urethra within the prostate. A fluid stream is directed outwardly from the fluid delivery element toward a wall of the urethral lumen. The fluid delivery element is moved to scan the fluid stream over the wall to remove a volume of tissue surrounding the lumen. The fluid may be combined with therapeutically active substances or with substances that increase resection efficiency. Fluid force may be adjusted to provide selective tissue resection such that soft tissue is removed while harder tissue is left undamaged. In order to gain a working space within the urethra, another fluid may be introduced to insufflate the urethra in the region of treatment.