Fluid Supply Interface Safety Valve for Cell Culture Overpressure

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Solution Overview

Problem

The existing fluid supply interfaces for cell culture systems are prone to damage due to undesired pressure increases when the supply valve fails to close and the discharge valve fails to open, leading to uncontrolled fluid leakage through gaps between coupling configurations.

Innovation Solution

Incorporating a safety valve that opens when a predetermined pressure difference is exceeded, allowing fluid to flow away from the conduit and into the discharge line, thereby reducing overpressure independently of the switching device operation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If the supply valve and discharge valve are controlled by a switching device, then the fluid flow can be directed to different cell culture containers, but the system becomes vulnerable to pressure buildup when valves fail to respond

Engineering Contradiction:
Improvefluid flow direction controlVSAvoidpressure control reliability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The safety valve operates autonomously based on pressure differential conditions, automatically opening to relieve overpressure without requiring external control signals or awareness of valve failure states. This self-regulating mechanism ensures system safety independent of the switching device's operational status.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The safety valve acts as an intermediary protective element between the fluid conduit and the discharge coupling configuration. It mediates the pressure control function by providing a passive fail-safe discharge path that activates when the primary control valves malfunction, preventing catastrophic pressure buildup.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If the discharge valve is controlled by the switching device, then discharge flow can be directed to different containers, but the system cannot prevent uncontrolled fluid leakage when the valve fails to open

Engineering Contradiction:
Improvedischarge flow direction controlVSAvoiduncontrolled fluid leakage
Core Design Contradiction:
Adaptability or versatilityVSObject-affected harmful factors

Solution Approach 1:

The safety valve converts the harmful effect of overpressure (which indicates valve failure) into a beneficial automatic discharge action. When pressure builds up due to valve malfunction, the safety valve detects this condition and activates to relieve the pressure, transforming the failure state into a controlled safety response.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The safety valve is pre-configured as a fail-safe mechanism that is ready to activate before catastrophic failure can occur. It provides a pre-established discharge path that activates when pressure exceeds a predetermined threshold, cushioning against the harmful effects of valve failure before they can cause damage to the system.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

3Reliability

If a safety valve is added to the fluid supply interface, then overpressure protection is improved, but the device complexity increases

Engineering Contradiction:
Improveoverpressure protectionVSAvoidvalve system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The safety valve is designed as a simple, inexpensive passive component with no complex control mechanisms. It uses basic pressure differential actuation and provides a reliable fail-safe function at minimal cost and complexity, making the added protection worthwhile despite the increased number of components.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution enhances the operational reliability of the fluid supply interface by effectively reducing overpressure and preventing damage from uncontrolled fluid leakage, ensuring safe and controlled fluid management in cell culture systems.

Implementation Method 1

at least one supply valve by means of which, depending on its position, a supply coupling configuration is capable of having fluid flow through it or is blocked for flow through it, the at least one supply valve being preloaded, preferably by magnetic force, into a blocking position

Methodology Applied
Scientific EffectMagnetic force: Magnetism

Implementation Method 2

at least one discharge valve, different from the supply valve, by means of which, depending on its position, a discharge coupling configuration is capable of having fluid flow through it or is blocked for flow through it, the at least one discharge valve likewise being preloaded into a closed position that prevents flow through it

Methodology Applied
Scientific EffectPressure difference: Pressure Gradient

Implementation Method 3

In some circumstances, in the context of pressure-induced forced opening of a supply valve, fluid can thereby be conveyed from a supply fluid line to the user coupling configuration

Methodology Applied
Scientific EffectPressure-induced forced opening: Pressure Gradient

Data Source

PatentUS11608487B2Fluid supply interface having a safety valve for a cell culture system, use of such a fluid supply interface for managing cell culture containers, and cell culture management system
Publication Date: 2023.03.21 HAMILTON BONADUZ AG
  • US11608487B2 patent drawing
  • US11608487B2 patent drawing
  • US11608487B2 patent drawing

AI summary

A fluid supply interface includes at least one supply coupling configuration, at least one discharge coupling configuration, at least one user coupling configuration, and a fluid conduit that connects the supply, discharge, and user coupling configurations to one another. A supply valve is capable of having fluid flow through it or is blocked for flow through it. A discharge valve is capable of having fluid flow through it or is blocked for flow through it. The supply valve is preloaded into a blocking position that prevents flow, and opens by means of a sufficiently large pressure difference between the two sides of the supply valve, against the preload force, for flow through in a direction from the supply coupling configuration toward the fluid conduit. The discharge valve likewise being preloaded into a closed position that prevents flow through it.