Fluidic Interface Compression Applicator for Leak-Tight Seals

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Solution Overview

Problem

Current microfluidic and nano-liquid chromatography systems face significant challenges in making reliable, leak-tight fluidic connections, which are often dependent on user skill and prone to issues like leakage, clogging, and high complexity, limiting their application in real-world diagnostics and analysis.

Innovation Solution

A system for making fluidic connections using a base, a tube, a compressible material, and a moveable compression applicator that creates a direct leak-resistant seal between the tube and a fluid receiving device, allowing for controlled compression to ensure a secure and reliable connection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fluidic connection methods are used, then user skill and expertise are required to make reliable connections, but this increases the complexity and difficulty of operation

Engineering Contradiction:
Improveconnection reliabilityVSAvoidease of connection
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

A compression applicator with a constraining feature acts as an intermediary tool to facilitate the connection process. The applicator compresses the tubing against the receiver port while the constraining feature prevents over-compression and misalignment, making the connection process reliable yet simple to operate.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system controls the compression parameter by limiting the maximum compression force through the constraining feature. This ensures consistent, reliable connections while preventing damage from excessive compression, thereby improving both reliability and ease of operation.

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If conventional fluidic connection methods are used, then connections are prone to leakage and clogging, but this worsens the reliability of the system

Engineering Contradiction:
Improveease of connectionVSAvoidleak resistance
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The compression applicator with constraining feature serves as a mediator that ensures proper compression force is applied to create leak-tight seals. The constraining feature guarantees consistent compression parameters, preventing both insufficient sealing (leakage) and excessive force (clogging).

Inventive Principle:
Principle #24Intermediary (Mediator)

3Manufacturing precision

If complex connection procedures are used, then more precise control can be achieved, but this increases the device complexity and user skill requirements

Engineering Contradiction:
Improveconnection precisionVSAvoidconnection system complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The constraining feature on the compression applicator acts as a mechanical intermediary that enforces precise connection parameters. It provides physical limits for compression depth and force, ensuring manufacturing precision without requiring complex control systems or high user skill.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Reliability

If high compression force is applied to ensure leak-tight connections, then seal quality improves, but this increases the risk of clogging and damage to the tube

Engineering Contradiction:
Improveseal qualityVSAvoidtube damage and clogging
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The constraining feature establishes an optimal compression parameter range by physically limiting the maximum compression force. This ensures sufficient force for leak-tight seals while preventing excessive force that would cause tube damage or clogging, thereby resolving the contradiction between seal quality and tube integrity.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides a robust and reliable method for creating leak-tight fluidic connections, reducing the complexity and user skill requirements, and enhancing the performance and reliability of microfluidic and nano-liquid chromatography systems by minimizing dead volumes and preventing leaks.

Implementation Method 1

a moveable compression applicator mountable to the base, the moveable compression applicator capable of exerting a force on the first end of the compressible material

Methodology Applied
Scientific EffectCompression: Compression

Implementation Method 2

a compressible material having a first end and a second end and surrounding the tube adjacent the first end of the tube

Methodology Applied
Scientific EffectElasticity: Elasticity

Data Source

PatentEP2718017B1Fluidic interface
Publication Date: 2020.08.05 CORSOLUTIONS INC
  • EP2718017B1 patent drawingFigure 1
  • EP2718017B1 patent drawingFigure 2
  • EP2718017B1 patent drawingFigure 3

AI summary

The invention provides for fluidic connections to be established between tubes, ports, fluidic components and fluidic devices. The leak-tight connections are formed through controlled, compressive forces and can be used for both low and high pressure applications.