Fluorescence Observation Device Dual-Substrate Imaging
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Solution Overview
Problem
Conventional fluorescence observation endoscopes face challenges in simultaneously achieving high sensitivity and wide-range observation due to the size constraints of imaging systems, particularly with the use of dichroic mirrors and laminated imaging devices, which struggle with weak fluorescence emission from ICG and require high light shielding rates that compromise image quality.
Innovation Solution
A fluorescence observation device with a light source that emits adjustable visible and excitation light intensities, an imaging device featuring a dielectric multilayer film filter to attenuate visible light, and a setting device to optimize light emission based on detected intensities, ensuring effective fluorescence detection without deteriorating image quality.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If a dichroic mirror is used to separate visible light and excitation light for simultaneous imaging, then imaging capability is improved, but the device size increases making it difficult to mount on the distal end
Solution Approach 1:
The imaging device is divided into two separate imaging units: a first imaging unit for capturing visible light and a second imaging unit for capturing fluorescence. This segmentation eliminates the need for a dichroic mirror to separate light paths, reducing the overall device size while maintaining dual imaging capability. Each imaging unit can be independently optimized for its specific wavelength range.
Solution Approach 2:
The patent transitions from a planar light separation approach using dichroic mirrors to a spatially separated approach where visible light and fluorescence are captured by distinct imaging units positioned at different locations. This dimensional reorganization allows for compact integration on the distal end without requiring complex optical separation components.
2Measurement precision
If a laminated imaging device with high light shielding rate is used to detect weak fluorescence, then detection sensitivity is improved, but visible light transmission is blocked compromising image quality
Solution Approach 1:
The imaging system is segmented into two independent paths: one for visible light imaging and another for fluorescence detection. This allows the fluorescence detection path to use high light shielding filters without affecting visible light transmission, as the visible light is captured separately by the first imaging unit. The segmentation resolves the trade-off between fluorescence sensitivity and visible light image quality.
Solution Approach 2:
The patent introduces an intermediary approach where visible light and fluorescence are separated at the source through dedicated imaging units rather than relying on a single imaging device with conflicting requirements. This intermediary separation allows each imaging unit to be optimized for its specific function without compromise.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution enables precise control of light intensities to enhance fluorescence detection accuracy and maintain image quality, even in varying conditions, while minimizing the size and complexity of the imaging system, thus facilitating wider range and more sensitive observations.
Implementation Method 1
an interlayer filter arranged between the first substrate and the second substrate, the first photoelectric conversion element being configured to detect light of a visible region within reflected light reflected from the object, the second photoelectric conversion element being configured to detect light of an infrared region within the reflected light transmitted through the first substrate, and the interlayer filter being configured to attenuate the light of the visible region transmitted through the first substrate
Implementation Method 2
a first substrate on which a plurality of first photoelectric conversion elements are formed, a second substrate on which a plurality of second photoelectric conversion elements are formed
Implementation Method 3
a light source device configured to irradiate an object with light including wavelength bands of visible light and excitation light
Implementation Method 4
ICG is a fluorescent material having affinity for a lesion such as cancer and is excited by light of an infrared region and emits fluorescence
Data Source
AI summary
A light source device configured to irradiate an object with visible light and excitation light, an imaging device including a first substrate on which a plurality of first photoelectric conversion elements configured to detect a visible light within reflected light from the object are formed, a second substrate on which a plurality of second photoelectric conversion elements configured to detect light of an infrared region within the reflected light transmitted through the first substrate are formed, and an interlayer filter configured to attenuate the light of the visible region transmitted through the first substrate, and a setting device configured to set a light emission intensity of the visible light radiated by the light source device so that first photoelectric conversion elements is able to detect the visible light and a detection value of light detected by second photoelectric conversion element become less than or equal to a predetermined value.