Fluorescent Compound for Rapid Phosgene and DCP Detection

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Solution Overview

Problem

Current methods lack a fast and accurate means to detect phosgene and diethyl chlorophosphate, particularly during the latent stage of exposure, posing risks due to their toxic and hazardous nature, and existing sensors are not sensitive enough to differentiate these substances from other chemical warfare agents or gases.

Innovation Solution

A compound represented by formula 1, which undergoes specific reactions to detect phosgene and diethyl chlorophosphate by changes in fluorescence and color development, allowing for rapid and selective detection in both gas and liquid phases with high sensitivity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional detection methods are used for phosgene, then detection can be performed, but the detection speed is slow and accuracy is insufficient, especially during the latent stage

Engineering Contradiction:
Improvedetection accuracyVSAvoiddetection time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent develops fluorescent chemical sensors that utilize changes in fluorescence intensity or wavelength as detection parameters. The sensor compounds undergo specific chemical reactions with phosgene, causing measurable changes in their fluorescent properties, enabling rapid and accurate detection within seconds of exposure

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces conventional mechanical or electrochemical detection systems with optical detection methods based on fluorescence. This substitution allows for more sensitive and faster detection by measuring light emission changes rather than relying on slower mechanical response systems

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Adaptability or versatility

If existing sensors are used to detect chemical warfare agents, then detection is possible, but the sensors cannot selectively differentiate phosgene from other CWAs or gases

Engineering Contradiction:
ImproveselectivityVSAvoiddetection accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent introduces specific fluorescent compound intermediaries that have selective affinity for phosgene. These intermediary compounds react specifically with phosgene through unique chemical mechanisms, producing fluorescent signals only when phosgene is present, thereby enabling selective detection amidst other chemical warfare agents or gases

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent designs sensor compounds with specific local chemical properties and functional groups that are tailored to interact with phosgene's unique molecular structure. This localized chemical specificity enables the sensor to distinguish phosgene from other CWAs based on their different molecular characteristics

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compound enables rapid detection of phosgene and diethyl chlorophosphate with nM sensitivity, facilitating quick identification and differentiation from other gases, thereby enhancing safety by providing a sensitive and selective detection method.

Implementation Method 1

a compound and a composition for detecting phosgene and DCP... by detecting the changes of fluorescence

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Implementation Method 2

by detecting the changes of fluorescence or color development

Methodology Applied
Scientific EffectColor development:

Data Source

PatentUS10640513B2Compound and composition for detecting phosgene and diethyl chlorophosphate
Publication Date: 2020.05.05 EWHA UNIV IND COLLABORATION FOUND
  • US10640513B2 patent drawing
  • US10640513B2 patent drawing
  • US10640513B2 patent drawing

AI summary

The present invention relates to a compound for detecting phosgene and DCP (diethyl chlorophosphate) and a composition for detecting phosgene and DCP (diethyl chlorophosphate) comprising the said compound. More precisely, the compound for detecting phosgene and DCP of the present invention can selectively detect phosgene and DCP either in the liquid phase of gas phase by detecting the changes of fluorescence and color development very quickly within a few seconds with nM sensitivity. Therefore, the compound can also be effectively used as an ingredient for the composition and kit for the detection of one or more materials selected from the group consisting of phosgene and DCP.