Aqueous Fluoride Composition with Cationic Polymer for Rapid Caries Prevention
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Solution Overview
Problem
Current fluoride treatment methods, such as fluoride gels and varnishes, either require lengthy application times or are labor-intensive and leave an unpleasant sensation, while also varying in efficacy and ease of use.
Innovation Solution
Aqueous oral care fluoride treatment compositions containing 0.5 wt-% to 4.8 wt-% of a water-soluble cationic nitrogen-containing polymer, 1.0 wt-% to 2.5 wt-% of sodium fluoride, and at least 60 wt-% water, which can be applied directly to the teeth or in a dental tray, providing rapid fluoride release and reducing dental caries incidence.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If fluoride gel/foam is used in a tray, then fluoride can be applied to teeth, but the treatment requires lengthy contact time (1-4 minutes) and complex application procedure with suction
Solution Approach 1:
The patent changes the chemical parameters of the fluoride composition by incorporating specific polymers (carboxymethyl cellulose, hydroxyethyl cellulose, or hydroxypropyl cellulose) in controlled amounts (0.1-5% by weight) to modify the release kinetics of fluoride. This allows the fluoride to be delivered effectively in a shorter time frame without compromising efficacy, resolving the contradiction between treatment reliability and time consumption.
Solution Approach 2:
The invention creates a composite fluoride composition by combining sodium fluoride with specific cellulose derivatives. This composite structure enables controlled fluoride release while maintaining stability, allowing for rapid yet effective treatment that reduces contact time compared to conventional gels while preserving fluoride efficacy.
2Ease of operation
If fluoride varnish is used, then fluoride application is simple and ingestion is reduced, but the treatment is labor intensive and leaves unpleasant sensation
Solution Approach 1:
The patent modifies the physical and chemical parameters of the fluoride composition by incorporating cellulose derivatives that alter the composition's texture, drying characteristics, and sensory properties. These parameter changes eliminate the unpleasant sensations associated with traditional varnishes while maintaining ease of application, allowing the composition to be painted on teeth smoothly without the dirty feeling patients experience with conventional varnishes.
3Object-affected harmful factors
If fluoride varnish is used, then fluoride ingestion is reduced, but the treatment requires precise application and is more labor intensive
Solution Approach 1:
The patent creates a self-regulating fluoride composition where the cellulose derivative polymer provides controlled release of fluoride ions. This self-service mechanism ensures that fluoride is delivered effectively to the teeth without requiring precise application techniques, reducing labor intensity while maintaining low ingestion levels. The composition essentially regulates its own fluoride delivery, making the application process more efficient.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The compositions offer similar fluoride efficacy to traditional methods in shorter times, reducing dental caries incidence and improving patient comfort with a more efficient and user-friendly application process.
Implementation Method 1
aqueous oral care fluoride treatment compositions containing 0.5 wt-% to 4.8 wt-% of a water-soluble cationic nitrogen-containing polymer
Data Source
AI summary
An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patients tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.5 wt-% to 4.8 wt-% of a water-soluble cationic N-containing polymer; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.