Fluoroscopy System Peak Detection for Biopsy Localization

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Solution Overview

Problem

Current fluoroscopy systems lack an efficient method to accurately locate and visualize affected areas for biopsy by integrating white-light and fluorescence imaging, leading to difficulties in precise positioning and differentiation of regions with varying fluorescence intensities.

Innovation Solution

A fluoroscopy system that combines white-light and fluorescence imaging by detecting fluorescence intensity peaks, generating a combined image, and allowing for superimposition of regions with high fluorescence intensity on the white-light image, enabling precise localization and differentiation of affected areas through peak detection and color coding.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If fluorescence imaging is used to locate affected areas, then the ability to identify abnormal regions is improved, but the precision of localization and differentiation of regions with varying fluorescence intensities deteriorates

Engineering Contradiction:
Improveability to identify affected areasVSAvoidprecision of localization and differentiation
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent combines white-light imaging and fluorescence imaging into a single integrated system. The image combining section merges the white-light image (which provides good anatomical detail and localization) with the fluorescence image (which provides functional information about affected areas). This allows simultaneous visualization of both structural and functional information, improving both identification reliability and localization precision without requiring separate systems or manual correlation.

Inventive Principle:
Principle #5Merging (Combining)

2Quantity of substance

If multiple regions with different fluorescence intensities are detected, then comprehensive coverage of affected areas is improved, but the clarity of visualization and differentiation between regions deteriorates

Engineering Contradiction:
Improvenumber of detected regionsVSAvoidclarity of visualization and differentiation
Core Design Contradiction:
Quantity of substanceVSLoss of information

Solution Approach 1:

The patent applies local quality by using color coding to differentiate between regions of varying fluorescence intensity. The coloring section assigns different colors to pixels based on their fluorescence intensity values, allowing multiple regions with different intensities to be visualized simultaneously with clear differentiation. This maintains comprehensive coverage of all affected areas while preserving the ability to distinguish between regions with different characteristics.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the accuracy of identifying and targeting affected areas for biopsy by providing a clear visualization of high-fluorescence regions on the white-light image, improving the precision of inspection and treatment.

Implementation Method 1

an illumination light source that emits white light and excitation light for irradiation of a subject; a white-light-image generating section that generates a white-light image by capturing the reflected light reflected on the subject irradiated with the white light emitted from the illumination light source; a fluorescence-image generating section that generates a fluorescence image by capturing fluorescence emitted from the subject irradiated with the excitation light emitted from the illumination light source

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentUS8440984B2Fluoroscopy system
Publication Date: 2013.05.14 OLYMPUS CORPORATION(JP)
  • US8440984B2 patent drawing
  • US8440984B2 patent drawing
  • US8440984B2 patent drawing

AI summary

Provided is a fluoroscopy system includes a light source device that emits white light and excitation light for irradiation of a subject; a white-light-image generating section that generates a white-light image by capturing the white light reflected from the subject; a fluorescence-image generating section that generates a fluorescence image by capturing fluorescence from the subject irradiated with the excitation light; an intensity-distribution generating section that generates a fluorescence intensity distribution of pixels of the fluorescence image; a peak-detecting section that detects a fluorescence-intensity peak in the fluorescence intensity distribution; a peak-count comparing section that calculates a count of the peak; an image-combining section that generates a combined image by superimposing a display representing a region including a pixel having the fluorescence intensity at the peak on the white-light image or the fluorescence image based on the peak count; and a monitor that displays the combined image.