Therapeutic Foam Mixing Device with Porous Mesh Screen

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Solution Overview

Problem

Current methods for generating therapeutic foam in medical and veterinary applications often require complex equipment and lack efficiency in mixing and dispensing processes, particularly in producing foams immediately prior to use from components like liquids and gases.

Innovation Solution

A method and device involving a syringe and mixing device with a three-way valve, mixing channel, supply channel, and delivery channel, utilizing a mixing element such as a mesh screen or sintered material to create therapeutic foam by compressing and releasing a plunger, allowing for efficient mixing and dispensing of foamable therapeutics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If complex equipment is used to generate therapeutic foam, then foam generation capability is achieved, but device complexity increases and efficiency decreases

Engineering Contradiction:
Improvefoam generation efficiencyVSAvoidequipment complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The device is divided into separate functional modules: a syringe for storing and pushing the foamable therapeutic, a mixing device with distinct channels (supply channel from syringe, mixing channel through mesh, delivery channel to patient), and a three-way valve for controlling flow paths. This segmentation allows each component to perform its specific function efficiently while keeping the overall system manageable and not overly complex.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A mesh screen or sintered material is introduced as an intermediary element in the mixing channel. This intermediary component facilitates efficient mixing of the foamable therapeutic with gas (air or medical gas) to create stable foam, while requiring minimal device complexity. The mesh acts as a passive mixing element that leverages fluid dynamics rather than requiring complex active mixing mechanisms.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If foam is prepared in advance, then availability is improved, but freshness and effectiveness decrease due to foam degradation over time

Engineering Contradiction:
Improvefoam freshness and effectivenessVSAvoidtime between preparation and use
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The foamable therapeutic is prepared and loaded into the syringe in advance, but the actual foam generation is deferred until the moment of use. The syringe is equipped with a mixing device that combines the foamable therapeutic with gas only when needed, ensuring maximum freshness and effectiveness. This preliminary preparation of components rather than the final product resolves the contradiction between availability and freshness.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The device enables on-demand parameter changes in the therapeutic formulation by controlling the mixing ratio and foam stability through the mesh screen characteristics. The foam characteristics (bubble size, stability, density) can be adjusted by selecting appropriate mesh parameters, allowing optimization for specific clinical applications while maintaining freshness through immediate preparation.

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If simple mixing is used, then device complexity is reduced, but foam quality and bubble size control deteriorate

Engineering Contradiction:
Improvebubble size control and foam qualityVSAvoidmixing device complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

A mesh screen or sintered material is employed in the mixing channel to control bubble size and foam quality. The porous structure of the mesh (with controlled pore sizes) directly influences the foam characteristics, enabling precise control over bubble diameter and distribution. This approach achieves high manufacturing precision through a relatively simple passive mixing mechanism rather than complex active systems.

Inventive Principle:
Principle #31Porous materials

Solution Approach 2:

The mesh screen parameters (pore size, mesh density, material properties) can be adjusted to optimize foam quality for different applications. By changing these physical parameters of the mixing element, precise control over bubble size and foam stability is achieved without requiring complex mechanical or electronic control systems, thus maintaining device simplicity while ensuring high precision.

Inventive Principle:
Principle #35Parameter changes

4Productivity

If rapid foam generation is implemented, then productivity is improved, but mixing completeness and foam consistency deteriorate

Engineering Contradiction:
Improvefoam generation speedVSAvoidfoam consistency and mixing completeness
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The foam generation process maintains continuous useful action through the three-way valve system that can rapidly switch between different flow paths. The mesh screen continuously mixes the foamable therapeutic with gas as it passes through, ensuring complete mixing and consistent foam quality even during rapid generation. The continuous flow through the porous mesh ensures uniform foam characteristics without interruption.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The device utilizes pneumatic principles by introducing gas (air or medical gas) through the mesh screen into the foamable therapeutic liquid, creating foam through gas dissolution and bubble formation. This pneumatic mechanism enables rapid foam generation while maintaining mixing completeness, as the gas-liquid interaction through the porous mesh is inherently efficient and continuous, producing consistent foam quality at high speeds.

Inventive Principle:
Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables the efficient on-demand generation of therapeutic foam with controlled bubble size and distribution, optimizing foam characteristics for specific applications by repeatedly plunging and releasing the plunger through the mixing device, ensuring consistent and effective delivery.

Implementation Method 1

a mixing element disposed in the mixing channel... the mixing element includes a mesh screen characterized by apertures of between about 100 μm and 500 μm; in some implementations, the mixing element includes a mesh screen characterized by apertures of between about 10 μm and 25 μm; in some implementations, the mixing element includes a sintered or porous material

Methodology Applied
Scientific EffectFoam generation through porous material: Porosity

Implementation Method 2

a plunger and spring disposed within the syringe body... plunging the plunger of the syringe to force foamable therapeutic through the supply channel, mixing channel and mixing element and into the mixing device, thereby causing the spring to be compressed; releasing force on the plunger of the syringe to allow the spring to force the foamable therapeutic back through the mixing channel, mixing element and supply channel and into the syringe, thereby creating a foamed therapeutic

Methodology Applied
Scientific EffectSpring elastic force: Spring

Data Source

PatentUS20230390159A1Foam-generating devices and methods
Publication Date: 2023.12.07 MOONSHOT MEDICAL LLC
  • US20230390159A1 patent drawing
  • US20230390159A1 patent drawing
  • US20230390159A1 patent drawing

AI summary

A kit may include a syringe; and a mixing device. The syringe may have a barrel, a plunger, a tip, and a foamable therapeutic disposed in the barrel. The mixing device may have (A) a syringe body and a mixing tip fluidly coupled to an interior of the syringe body, and a plunger and spring disposed within the syringe body; (B) a mixing channel, a supply channel and a delivery channel; wherein one end of the mixing channel is coupled to the mixing tip and one end of the supply channel includes a connector for removably coupling to the syringe; (C) a three-way valve that is configured to selectively couple an opposite end of the mixing channel, an opposite end of the supply channel and the delivery channel to one or more of the other; and (D) a mixing element disposed in the mixing channel.