Foamy Powder Composition for Bitterness Masking and Drug Dissolution
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Solution Overview
Problem
Existing medication-assisting foods fail to effectively mask bitterness and ensure drug dissolution, particularly in aqueous solvents, with issues such as poor dispersibility and instability in conventional methods.
Innovation Solution
A powder composition comprising carbohydrate, acid component, carbonate component, and foam stabilizer, which when mixed with water, forms a foamy food product that envelops and masks bitterness while ensuring drug dissolution.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If conventional medication-assisting foods are used to mask bitterness, then the masking effect is provided, but the dispersibility in aqueous solvents is poor and drug dissolution is not ensured
Solution Approach 1:
The invention changes the physical state and compositional parameters of the medication-assisting food by using a foamy structure with specific void ratio (0.2-0.8) and controlled water content (5-50%), thereby improving both masking effect and drug dissolution simultaneously
Solution Approach 2:
The invention creates a composite structure combining food material, drug, and air in a foamy configuration, where the foam structure acts as a carrier that both masks bitterness and facilitates drug dissolution in aqueous solvents
2Ease of operation
If granular jelly drink or powder composition is used, then the drug is taken, but the masking effect is not stable and bitterness remains perceptible
Solution Approach 1:
The foamy food structure acts as an intermediary carrier that envelops the drug particles, preventing direct contact with bitter taste receptors while maintaining stable masking effect throughout the drug dissolution process
3Object-affected harmful factors
If chocolate-based medication aid is used, then the bitterness is masked, but the dispersibility in aqueous solvents is poor
Solution Approach 1:
The invention changes the chemical composition parameters by replacing chocolate-based materials with food materials having specific properties (carbohydrate content, moisture content, foam stability), enabling both effective masking and excellent dispersibility in aqueous solvents
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The foamy food product provides a stable masking effect and excellent dispersibility, allowing for effective drug dissolution as per Japanese Pharmacopoeia standards, reducing bitterness perception and improving drug intake comfort.
Implementation Method 1
a foam stabilizer
Implementation Method 2
an acid component, a carbonate component
Data Source
AI summary
Provided is a powder composition that can be made into a foamy food product exhibiting a masking effect and being highly dispersible in an aqueous solvent. The powder composition is to be made into a foamy food product by mixing with water. The powder composition comprises the following components (A) to (D): (A) a carbohydrate; (B) an acid component; (C) a carbonate component; and (D) a foam stabilizer.