Noninvasive Glucose Analyzer Using Force-Optic Tissue Modification
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Solution Overview
Problem
There is a need for a noninvasive method to determine glucose concentration in the human body effectively, as existing technologies have limitations in accurately measuring glucose levels without invasive procedures.
Innovation Solution
A noninvasive glucose concentration analyzer system using applied force-optic technology, which applies physical forces to alter tissue properties, allowing spectrometers to measure glucose levels through changes in absorbance and scattering of photons in the visible and near-infrared regions, utilizing multiple spectrometer units and a controller to process signals for accurate glucose concentration determination.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If noninvasive optical methods are used to measure glucose concentration, then patient comfort and safety are improved, but measurement precision deteriorates due to interference from tissue properties
Solution Approach 1:
The patent applies force to the tissue to change its physical parameters (density, refractive index, molecular packing) temporarily, which modifies the optical properties and enhances the glucose-specific spectral signal. This allows noninvasive measurement while improving precision by dynamically adjusting tissue parameters to favor glucose detection.
Solution Approach 2:
The applied force acts as an intermediary that modifies the tissue state to improve the interaction between light and glucose molecules. By introducing this mechanical intermediary, the system overcomes the limitation of direct optical measurement through tissue, enabling accurate noninvasive glucose concentration determination.
2Measurement precision
If multiple spectrometer units are used to improve measurement accuracy, then measurement precision is improved, but device complexity increases
Solution Approach 1:
The system divides the measurement task into multiple spectral regions by using multiple spectrometer units, each optimized for specific wavelength ranges. This segmentation allows simultaneous collection of complementary spectral information, improving glucose measurement precision while distributing the complexity across modular components.
Solution Approach 2:
The patent extends the measurement from a single spectral dimension to multiple spectral dimensions by employing multiple spectrometer units covering different wavelength ranges. This multi-dimensional spectral analysis provides redundant and complementary information, enhancing measurement accuracy despite increased system complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables noninvasive and accurate measurement of glucose levels by altering tissue properties with applied forces, enhancing the detection of glucose concentration through changes in absorbance and scattering, providing a reliable and minimally invasive method for glucose monitoring.
Implementation Method 1
measure glucose levels through changes in absorbance and scattering of photons
Implementation Method 2
measure glucose levels through changes in absorbance and scattering of photons
Implementation Method 3
applies physical forces to alter tissue properties, allowing spectrometers to measure glucose levels through changes in absorbance and scattering
Data Source
AI summary
The invention comprises a method and apparatus for noninvasively determining state of a person, comprising the steps of: providing an analyzer comprising a first and second spectrometer unit and a main controller subsystem; replaceably attaching the first spectrometer unit to the person at a first illumination zone; the first spectrometer unit delivering first photons, from first illumination optics, along a first mean z-axis optical path normal to a first x/y-plane tangentially contacting the first illumination zone of the person; replaceably attaching a second spectrometer unit to the person at a second illumination zone; the second spectrometer delivering second photons, from second illumination optics, along a second mean z-axis optical path perpendicular to a second x/y-plane tangentially contacting the second illumination zone of the skin, the first x/y-plane noncoplanar with the second x/y-plane; and the main controller processing detected signals to generate at least one measure of state of the person.


