Formic Acid Extraction Using Linear Primary Alcohols

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Solution Overview

Problem

Current methods for separating formic acid from a reaction mixture containing a polyoxometalate ion are complex and often inactivate the catalyst, requiring multiple distillation steps and specific solvents that can oxidize primary alcohols, making efficient extraction challenging.

Innovation Solution

A method using linear primary alcohols with 5 to 12 carbon atoms in a protic solvent to extract formic acid from a reaction mixture, allowing for selective separation of formic acid under favorable reaction conditions without inactivating the catalyst, and enabling in-situ extraction during formic acid production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If ether or amide is used for extraction, then formic acid can be separated, but the process becomes complex requiring multiple distillation steps

Engineering Contradiction:
Improveformic acid separation efficiencyVSAvoidextraction process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent extracts formic acid from the reaction mixture using a linear primary alcohol, separating it from the polyoxometalate catalyst and other components in a single extraction step, eliminating the need for complex multi-step distillation processes

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the extraction parameter by using linear primary alcohols with 5 to 12 carbon atoms, which have optimal solubility characteristics for formic acid, achieving efficient separation without requiring complex process equipment

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If conventional extraction solvents are used, then formic acid can be extracted, but the catalyst is inactivated

Engineering Contradiction:
Improveformic acid extraction efficiencyVSAvoidcatalyst activity
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The linear primary alcohol acts as an intermediary extractant that selectively dissolves formic acid without interacting with or deactivating the polyoxometalate catalyst, allowing simultaneous preservation of catalyst activity and efficient acid extraction

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical parameter of the extraction solvent to linear primary alcohols with 5 to 12 carbon atoms, which have the specific property of being unable to oxidize primary alcohols under reaction conditions, thus preserving catalyst activity while maintaining extraction efficiency

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If oxidation conditions are applied to extract formic acid, then separation can be achieved, but primary alcohols are cleaved

Engineering Contradiction:
Improveformic acid separationVSAvoidprimary alcohol degradation
Core Design Contradiction:
Manufacturing precisionVSLoss of substance

Solution Approach 1:

The patent changes the chemical stability parameter by selecting linear primary alcohols with 5 to 12 carbon atoms as extractants, which resist oxidation and C-C bond cleavage under the reaction conditions, preventing substance loss while achieving formic acid separation

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach effectively separates formic acid while preserving the catalyst's activity, achieving high selectivity and efficiency in formic acid extraction, as demonstrated by the use of 1-hexanol and 1-heptanol, which show high distribution coefficients and selectivity for formic acid, even during the oxidation of organic substances.

Implementation Method 1

A method using linear primary alcohols with 5 to 12 carbon atoms in a protic solvent to extract formic acid from a reaction mixture

Methodology Applied
Scientific EffectLiquid-liquid extraction: Liquid-Liquid Extraction

Implementation Method 2

The polyoxometalate ion mentioned serves as a catalyst

Methodology Applied
Scientific EffectCatalysis: Catalysis

Implementation Method 3

an oxidative cleavage of C-C bonds of primary alcohols and vicinal diols

Methodology Applied
Scientific EffectOxidation: Oxidation

Data Source

PatentEP3247695B1Method for isolating of formic acid from a reaction mixture
Publication Date: 2019.03.06 OXFA GMBH

AI summary

The invention relates to a method for separating formic acid from a reaction mixture which comprises, in addition to formic acid, a polyoxometalate ion of general formula [PMoxVyO40]n-, where 6 ≤ x ≤ 11, 1 ≤ y ≤ 6, x + y = 12 and 3 < n < 10, where n, x and y are each integers, wherein the separation occurs by means of an extraction using a linear primary alcohol, wherein the carbon chain of the alcohol comprises 5 to 12 carbon atoms, and the reaction mixture is present in a protic solvent.